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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLF
All Species:
17.88
Human Site:
S54
Identified Species:
56.19
UniProt:
Q16534
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16534
NP_002117.1
295
33199
S54
E
K
K
L
D
D
E
S
N
S
P
T
V
P
Q
Chimpanzee
Pan troglodytes
XP_001171681
301
33665
S54
E
K
K
L
D
D
E
S
N
S
P
T
V
P
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852892
295
33196
S54
E
K
K
L
D
D
E
S
N
S
P
T
V
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW74
295
33130
S54
G
K
K
L
D
D
E
S
S
S
P
T
V
P
Q
Rat
Rattus norvegicus
Q64709
295
33095
S54
G
K
K
L
D
D
G
S
N
S
P
T
V
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519820
263
29264
Y44
I
W
D
K
T
I
P
Y
D
G
E
S
F
H
L
Chicken
Gallus gallus
Q92172
319
34936
A74
K
L
E
E
D
E
A
A
A
A
S
T
M
A
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94126
211
23114
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.6
N.A.
99.3
N.A.
97.6
96.9
N.A.
47.4
49.5
N.A.
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
Protein Similarity:
100
90.6
N.A.
100
N.A.
98.6
97.9
N.A.
62.7
64.2
N.A.
N.A.
N.A.
N.A.
N.A.
34.5
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
86.6
N.A.
13.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
13
13
13
13
0
0
0
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
75
63
0
0
13
0
0
0
0
0
0
% D
% Glu:
38
0
13
13
0
13
50
0
0
0
13
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
25
0
0
0
0
0
13
0
0
13
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% H
% Ile:
13
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% I
% Lys:
13
63
63
13
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
13
0
63
0
0
0
0
0
0
0
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
13
0
0
0
63
0
0
63
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
63
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
63
13
63
13
13
0
0
0
% S
% Thr:
0
0
0
0
13
0
0
0
0
0
0
75
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
63
0
13
% V
% Trp:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _