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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP2R5E All Species: 44.55
Human Site: Y230 Identified Species: 81.67
UniProt: Q16537 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16537 NP_006237.1 467 54699 Y230 N I F L R F V Y E T E H F N G
Chimpanzee Pan troglodytes XP_001151388 673 75031 Y464 N I F L R F I Y E T E H F N G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_865670 487 56972 Y230 N I F L R F V Y E T E H F N G
Cat Felis silvestris
Mouse Mus musculus Q61151 467 54695 Y230 N I F L R F V Y E T E H F N G
Rat Rattus norvegicus NP_001100210 429 50328 F225 R K Q I N N I F L S I I N G F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506784 467 54655 Y230 N I F L R F V Y E T E H F N G
Chicken Gallus gallus XP_419432 476 55266 Y228 N I F L R F I Y E T E H F N G
Frog Xenopus laevis NP_001083870 467 54661 Y230 N I F L R F V Y E T E H F N G
Zebra Danio Brachydanio rerio NP_919396 468 54570 Y230 N I F L C F V Y E T E R F N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651569 524 59708 Y225 N I F L R F I Y E T E H F N G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780697 432 50137 Y227 H I F L R F I Y E T E H F N G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU89 510 58740 F281 N I F Y R F V F E T E K H N G
Baker's Yeast Sacchar. cerevisiae P38903 757 85316 Y462 N I F L Q F I Y E T E K F N G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.8 N.A. 95.8 N.A. 99.7 91.6 N.A. 99.7 76 98.2 90.1 N.A. 67.3 N.A. N.A. 70.2
Protein Similarity: 100 60.4 N.A. 95.8 N.A. 100 91.8 N.A. 99.7 88.6 99.7 95.3 N.A. 78.6 N.A. N.A. 81.8
P-Site Identity: 100 93.3 N.A. 100 N.A. 100 0 N.A. 100 93.3 100 86.6 N.A. 93.3 N.A. N.A. 86.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 26.6 N.A. 100 100 100 86.6 N.A. 100 N.A. N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. 50 36.9 N.A.
Protein Similarity: N.A. N.A. N.A. 65.2 47.8 N.A.
P-Site Identity: N.A. N.A. N.A. 73.3 80 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 93 0 93 0 0 0 0 % E
% Phe: 0 0 93 0 0 93 0 16 0 0 0 0 85 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 93 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 70 8 0 0 % H
% Ile: 0 93 0 8 0 0 47 0 0 0 8 8 0 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 0 16 0 0 0 % K
% Leu: 0 0 0 85 0 0 0 0 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 85 0 0 0 8 8 0 0 0 0 0 0 8 93 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 77 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 93 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 54 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 85 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _