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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAPK14 All Species: 23.43
Human Site: S2 Identified Species: 42.96
UniProt: Q16539 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16539 NP_001306.1 360 41293 S2 _ _ _ _ _ _ M S Q E R P T F Y
Chimpanzee Pan troglodytes Q95NE7 360 41475 S2 _ _ _ _ _ _ M S Q E R P T F Y
Rhesus Macaque Macaca mulatta XP_001112423 329 37756 F2 _ _ _ _ _ _ F F P F F L L S A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P47811 360 41269 S2 _ _ _ _ _ _ M S Q E R P T F Y
Rat Rattus norvegicus P70618 360 41303 S2 _ _ _ _ _ _ M S Q E R P T F Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232616 360 41440 S2 _ _ _ _ _ _ M S Q E R P K F Y
Frog Xenopus laevis P47812 361 41700 S3 _ _ _ _ _ M S S N Q S Y V F Y
Zebra Danio Brachydanio rerio Q9DGE2 361 41614 Q3 _ _ _ _ _ M S Q K E R P T F Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O61443 365 42080 S2 _ _ _ _ _ _ M S R K M A K F Y
Honey Bee Apis mellifera XP_395384 360 41360 P2 _ _ _ _ _ _ M P Q F H K V E I
Nematode Worm Caenorhab. elegans Q17446 377 43900 P13 T M D H I L H P T P R E G Y Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32485 435 48840 T3 _ _ _ _ _ M T T N E E F I R T
Red Bread Mold Neurospora crassa Q96TL5 358 41225 A2 _ _ _ _ _ _ M A E F I R A Q I
Conservation
Percent
Protein Identity: 100 96.1 89.4 N.A. N.A. 99.4 98.6 N.A. N.A. 96.3 88.3 85.8 N.A. 68.4 75 62.8 N.A.
Protein Similarity: 100 97.7 90.8 N.A. N.A. 99.4 99.1 N.A. N.A. 98.6 94.7 92.2 N.A. 80.2 85 76.6 N.A.
P-Site Identity: 100 100 0 N.A. N.A. 100 100 N.A. N.A. 88.8 30 60 N.A. 44.4 22.2 13.3 N.A.
P-Site Similarity: 100 100 0 N.A. N.A. 100 100 N.A. N.A. 88.8 40 70 N.A. 66.6 22.2 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 42.9 50.5
Protein Similarity: N.A. N.A. N.A. N.A. 57.9 69.4
P-Site Identity: N.A. N.A. N.A. N.A. 10 11.1
P-Site Similarity: N.A. N.A. N.A. N.A. 20 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 0 8 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 54 8 8 0 8 0 % E
% Phe: 0 0 0 0 0 0 8 8 0 24 8 8 0 62 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 8 0 0 8 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 8 0 8 0 16 % I
% Lys: 0 0 0 0 0 0 0 0 8 8 0 8 16 0 0 % K
% Leu: 0 0 0 0 0 8 0 0 0 0 0 8 8 0 0 % L
% Met: 0 8 0 0 0 24 62 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 16 8 8 0 47 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 47 8 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 54 8 0 8 0 % R
% Ser: 0 0 0 0 0 0 16 54 0 0 8 0 0 8 0 % S
% Thr: 8 0 0 0 0 0 8 8 8 0 0 0 39 0 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 70 % Y
% Spaces: 93 93 93 93 93 70 0 0 0 0 0 0 0 0 0 % _