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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK14
All Species:
30.91
Human Site:
S28
Identified Species:
56.67
UniProt:
Q16539
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16539
NP_001306.1
360
41293
S28
P
E
R
Y
Q
N
L
S
P
V
G
S
G
A
Y
Chimpanzee
Pan troglodytes
Q95NE7
360
41475
S28
P
E
R
Y
Q
N
L
S
P
V
G
S
G
A
Y
Rhesus Macaque
Macaca mulatta
XP_001112423
329
37756
F28
V
K
K
L
S
R
P
F
Q
S
I
I
H
A
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P47811
360
41269
S28
P
E
R
Y
Q
N
L
S
P
V
G
S
G
A
Y
Rat
Rattus norvegicus
P70618
360
41303
S28
P
E
R
Y
Q
N
L
S
P
V
G
S
G
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232616
360
41440
S28
P
E
R
Y
Q
N
L
S
P
V
G
S
G
A
Y
Frog
Xenopus laevis
P47812
361
41700
T29
P
D
R
Y
Q
N
L
T
P
V
G
S
G
A
Y
Zebra Danio
Brachydanio rerio
Q9DGE2
361
41614
S29
P
V
Q
Y
Q
N
L
S
P
V
G
S
G
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61443
365
42080
Q28
P
E
T
Y
Q
N
L
Q
P
V
G
Q
G
A
Y
Honey Bee
Apis mellifera
XP_395384
360
41360
S28
Q
M
L
T
P
V
G
S
G
A
Y
G
Q
V
C
Nematode Worm
Caenorhab. elegans
Q17446
377
43900
T39
P
N
Y
Y
I
N
L
T
P
I
G
T
G
A
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32485
435
48840
V29
R
Y
N
D
L
N
P
V
G
M
G
A
F
G
L
Red Bread Mold
Neurospora crassa
Q96TL5
358
41225
M28
S
D
L
Q
P
V
G
M
G
A
F
G
L
V
C
Conservation
Percent
Protein Identity:
100
96.1
89.4
N.A.
N.A.
99.4
98.6
N.A.
N.A.
96.3
88.3
85.8
N.A.
68.4
75
62.8
N.A.
Protein Similarity:
100
97.7
90.8
N.A.
N.A.
99.4
99.1
N.A.
N.A.
98.6
94.7
92.2
N.A.
80.2
85
76.6
N.A.
P-Site Identity:
100
100
6.6
N.A.
N.A.
100
100
N.A.
N.A.
100
86.6
86.6
N.A.
80
6.6
60
N.A.
P-Site Similarity:
100
100
20
N.A.
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
80
6.6
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
42.9
50.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
57.9
69.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
16
0
8
0
77
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% C
% Asp:
0
16
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
16
0
24
0
77
16
70
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
8
8
8
0
0
0
% I
% Lys:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
16
8
8
0
70
0
0
0
0
0
8
0
8
% L
% Met:
0
8
0
0
0
0
0
8
0
8
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
77
0
0
0
0
0
0
0
0
0
% N
% Pro:
70
0
0
0
16
0
16
0
70
0
0
0
0
0
0
% P
% Gln:
8
0
8
8
62
0
0
8
8
0
0
8
8
0
0
% Q
% Arg:
8
0
47
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
8
0
0
54
0
8
0
54
0
0
0
% S
% Thr:
0
0
8
8
0
0
0
16
0
0
0
8
0
0
0
% T
% Val:
8
8
0
0
0
16
0
8
0
62
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
70
0
0
0
0
0
0
8
0
0
0
70
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _