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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAPK14 All Species: 47.88
Human Site: Y182 Identified Species: 87.78
UniProt: Q16539 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16539 NP_001306.1 360 41293 Y182 T D D E M T G Y V A T R W Y R
Chimpanzee Pan troglodytes Q95NE7 360 41475 Y182 T D D E M T G Y V A T R W Y R
Rhesus Macaque Macaca mulatta XP_001112423 329 37756 M167 P E I M L N W M H Y N Q T V D
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P47811 360 41269 Y182 T D D E M T G Y V A T R W Y R
Rat Rattus norvegicus P70618 360 41303 Y182 T D D E M T G Y V A T R W Y R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232616 360 41440 Y182 T D D E M T G Y V A T R W Y R
Frog Xenopus laevis P47812 361 41700 Y183 T D E E M T G Y V A T R W Y R
Zebra Danio Brachydanio rerio Q9DGE2 361 41614 Y183 T D D E M T G Y V A T R W Y R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O61443 365 42080 Y185 A E S E M T G Y V A T R W Y R
Honey Bee Apis mellifera XP_395384 360 41360 Y178 T E N E M T G Y V A T R W Y R
Nematode Worm Caenorhab. elegans Q17446 377 43900 Y193 T D S E M T G Y V A T R W Y R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32485 435 48840 Y176 Q D P Q M T G Y V S T R Y Y R
Red Bread Mold Neurospora crassa Q96TL5 358 41225 Y173 Q D P Q M T G Y V S T R Y Y R
Conservation
Percent
Protein Identity: 100 96.1 89.4 N.A. N.A. 99.4 98.6 N.A. N.A. 96.3 88.3 85.8 N.A. 68.4 75 62.8 N.A.
Protein Similarity: 100 97.7 90.8 N.A. N.A. 99.4 99.1 N.A. N.A. 98.6 94.7 92.2 N.A. 80.2 85 76.6 N.A.
P-Site Identity: 100 100 0 N.A. N.A. 100 100 N.A. N.A. 100 93.3 100 N.A. 80 86.6 93.3 N.A.
P-Site Similarity: 100 100 20 N.A. N.A. 100 100 N.A. N.A. 100 100 100 N.A. 86.6 100 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 42.9 50.5
Protein Similarity: N.A. N.A. N.A. N.A. 57.9 69.4
P-Site Identity: N.A. N.A. N.A. N.A. 66.6 66.6
P-Site Similarity: N.A. N.A. N.A. N.A. 86.6 86.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 77 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 77 47 0 0 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 24 8 77 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 93 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 8 93 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 0 0 0 0 8 0 0 0 0 % N
% Pro: 8 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 16 0 0 16 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 93 0 0 93 % R
% Ser: 0 0 16 0 0 0 0 0 0 16 0 0 0 0 0 % S
% Thr: 70 0 0 0 0 93 0 0 0 0 93 0 8 0 0 % T
% Val: 0 0 0 0 0 0 0 0 93 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 77 0 0 % W
% Tyr: 0 0 0 0 0 0 0 93 0 8 0 0 16 93 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _