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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK7
All Species:
22.42
Human Site:
S722
Identified Species:
41.11
UniProt:
Q16549
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16549
NP_004707.2
785
86247
S722
E
E
G
T
E
L
E
S
V
P
L
C
S
S
K
Chimpanzee
Pan troglodytes
XP_508776
785
86375
S722
E
E
G
T
E
L
E
S
V
P
L
C
S
S
K
Rhesus Macaque
Macaca mulatta
XP_001093007
786
86480
S722
E
E
G
T
E
L
E
S
V
P
L
C
S
S
K
Dog
Lupus familis
XP_850224
787
86625
S722
E
E
G
T
E
L
E
S
V
P
L
C
N
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61139
770
84397
E720
K
D
A
G
T
A
L
E
S
M
P
L
C
S
S
Rat
Rattus norvegicus
Q62849
783
85580
S721
E
V
G
T
A
L
E
S
M
P
L
C
S
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025528
629
69561
V579
A
D
W
T
F
S
T
V
R
C
W
G
E
E
A
Frog
Xenopus laevis
P29119
783
86425
S689
E
S
P
T
L
K
D
S
S
H
D
Y
V
A
R
Zebra Danio
Brachydanio rerio
NP_001076494
709
77055
D659
E
V
A
L
T
H
W
D
W
R
G
G
C
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26016
1269
138609
S1039
L
E
P
Y
E
N
S
S
P
K
G
K
P
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
C840
G
K
G
S
I
G
Y
C
R
P
C
C
P
E
G
Sea Urchin
Strong. purpuratus
XP_789974
1055
115221
S903
Q
T
T
C
T
E
Q
S
T
L
L
V
N
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
D729
S
E
Y
D
S
T
L
D
N
G
T
S
G
I
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.2
91.1
N.A.
85.3
87.3
N.A.
N.A.
63
37.3
59.6
N.A.
25.6
N.A.
29.1
36
Protein Similarity:
100
99.2
98.7
94.9
N.A.
89.5
91.7
N.A.
N.A.
69.5
52.8
70.9
N.A.
37.8
N.A.
43.7
48.5
P-Site Identity:
100
100
100
93.3
N.A.
6.6
80
N.A.
N.A.
6.6
20
6.6
N.A.
20
N.A.
20
20
P-Site Similarity:
100
100
100
100
N.A.
20
86.6
N.A.
N.A.
13.3
40
13.3
N.A.
26.6
N.A.
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
0
8
8
0
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
8
0
0
0
8
0
8
8
47
16
0
0
% C
% Asp:
0
16
0
8
0
0
8
16
0
0
8
0
0
0
0
% D
% Glu:
54
47
0
0
39
8
39
8
0
0
0
0
8
16
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
47
8
0
8
0
0
0
8
16
16
8
0
8
% G
% His:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
8
8
0
0
0
8
0
0
0
8
0
8
0
8
39
% K
% Leu:
8
0
0
8
8
39
16
0
0
8
47
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
0
0
0
16
0
0
% N
% Pro:
0
0
16
0
0
0
0
0
8
47
8
0
16
0
0
% P
% Gln:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
16
8
0
0
0
0
16
% R
% Ser:
8
8
0
8
8
8
8
62
16
0
0
8
31
54
8
% S
% Thr:
0
8
8
54
24
8
8
0
8
0
8
0
0
0
8
% T
% Val:
0
16
0
0
0
0
0
8
31
0
0
8
8
8
0
% V
% Trp:
0
0
8
0
0
0
8
0
8
0
8
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _