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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK7
All Species:
6.06
Human Site:
T49
Identified Species:
11.11
UniProt:
Q16549
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16549
NP_004707.2
785
86247
T49
G
G
P
D
G
Q
G
T
G
G
P
S
W
A
V
Chimpanzee
Pan troglodytes
XP_508776
785
86375
P49
G
G
P
D
G
Q
G
P
G
G
P
S
W
A
V
Rhesus Macaque
Macaca mulatta
XP_001093007
786
86480
P49
G
G
P
D
G
Q
G
P
G
G
P
S
W
A
V
Dog
Lupus familis
XP_850224
787
86625
P49
D
R
P
G
A
Q
G
P
G
G
L
S
W
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61139
770
84397
T48
G
G
L
D
I
L
G
T
G
G
L
S
W
A
V
Rat
Rattus norvegicus
Q62849
783
85580
A48
G
G
L
D
T
L
G
A
G
G
L
S
W
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025528
629
69561
Frog
Xenopus laevis
P29119
783
86425
S37
N
T
W
A
A
H
I
S
G
G
S
A
E
A
D
Zebra Danio
Brachydanio rerio
NP_001076494
709
77055
Q37
R
S
W
A
V
Q
L
Q
P
D
S
L
S
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26016
1269
138609
H230
N
N
N
H
I
V
G
H
Y
T
H
T
W
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
L71
H
V
K
G
D
P
F
L
D
T
H
Y
F
L
Y
Sea Urchin
Strong. purpuratus
XP_789974
1055
115221
S115
H
Q
L
D
Q
D
S
S
N
V
P
R
D
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
R62
W
K
Y
E
H
D
V
R
G
L
P
N
H
Y
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.2
91.1
N.A.
85.3
87.3
N.A.
N.A.
63
37.3
59.6
N.A.
25.6
N.A.
29.1
36
Protein Similarity:
100
99.2
98.7
94.9
N.A.
89.5
91.7
N.A.
N.A.
69.5
52.8
70.9
N.A.
37.8
N.A.
43.7
48.5
P-Site Identity:
100
93.3
93.3
60
N.A.
73.3
66.6
N.A.
N.A.
0
20
6.6
N.A.
26.6
N.A.
0
13.3
P-Site Similarity:
100
93.3
93.3
60
N.A.
73.3
66.6
N.A.
N.A.
0
33.3
13.3
N.A.
33.3
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
16
0
0
8
0
0
0
8
0
62
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
47
8
16
0
0
8
8
0
0
8
0
8
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% F
% Gly:
39
39
0
16
24
0
54
0
62
54
0
0
0
0
0
% G
% His:
16
0
0
8
8
8
0
8
0
0
16
0
8
0
0
% H
% Ile:
0
0
0
0
16
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
24
0
0
16
8
8
0
8
24
8
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
8
8
0
0
0
0
0
8
0
0
8
0
0
0
% N
% Pro:
0
0
31
0
0
8
0
24
8
0
39
0
0
0
0
% P
% Gln:
0
8
0
0
8
39
0
8
0
0
0
0
0
0
0
% Q
% Arg:
8
8
0
0
0
0
0
8
0
0
0
8
0
0
0
% R
% Ser:
0
8
0
0
0
0
8
16
0
0
16
47
8
8
0
% S
% Thr:
0
8
0
0
8
0
0
16
0
16
0
8
0
0
0
% T
% Val:
0
8
0
0
8
8
8
0
0
8
0
0
0
0
62
% V
% Trp:
8
0
16
0
0
0
0
0
0
0
0
0
54
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
8
0
0
8
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _