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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK7
All Species:
16.06
Human Site:
T743
Identified Species:
29.44
UniProt:
Q16549
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16549
NP_004707.2
785
86247
T743
T
E
S
R
G
P
P
T
T
S
D
L
L
A
P
Chimpanzee
Pan troglodytes
XP_508776
785
86375
T743
T
E
S
R
G
P
P
T
T
S
D
L
L
A
P
Rhesus Macaque
Macaca mulatta
XP_001093007
786
86480
T743
T
E
S
R
G
P
P
T
T
S
D
L
L
V
P
Dog
Lupus familis
XP_850224
787
86625
T743
T
E
R
E
G
P
P
T
T
S
D
P
L
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61139
770
84397
T741
D
S
E
H
G
D
C
T
T
A
S
S
F
L
A
Rat
Rattus norvegicus
Q62849
783
85580
T742
S
E
H
G
D
C
T
T
A
S
S
L
L
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025528
629
69561
Q600
V
I
R
D
T
G
D
Q
S
L
R
S
G
T
L
Frog
Xenopus laevis
P29119
783
86425
L710
I
V
A
I
L
S
C
L
F
I
I
V
V
F
G
Zebra Danio
Brachydanio rerio
NP_001076494
709
77055
D680
G
Y
S
R
L
S
R
D
E
A
Q
T
D
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26016
1269
138609
P1060
F
E
V
D
L
F
K
P
T
N
G
G
N
S
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
D861
C
E
D
C
S
K
P
D
P
T
L
L
I
D
S
Sea Urchin
Strong. purpuratus
XP_789974
1055
115221
L924
P
T
K
L
P
E
T
L
H
S
N
F
D
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
D750
D
F
D
F
D
L
S
D
E
D
H
L
A
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.2
91.1
N.A.
85.3
87.3
N.A.
N.A.
63
37.3
59.6
N.A.
25.6
N.A.
29.1
36
Protein Similarity:
100
99.2
98.7
94.9
N.A.
89.5
91.7
N.A.
N.A.
69.5
52.8
70.9
N.A.
37.8
N.A.
43.7
48.5
P-Site Identity:
100
100
93.3
80
N.A.
20
46.6
N.A.
N.A.
0
0
13.3
N.A.
13.3
N.A.
20
6.6
P-Site Similarity:
100
100
93.3
80
N.A.
26.6
53.3
N.A.
N.A.
6.6
20
20
N.A.
26.6
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
8
16
0
0
8
31
8
% A
% Cys:
8
0
0
8
0
8
16
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
16
16
16
8
8
24
0
8
31
0
16
8
0
% D
% Glu:
0
54
8
8
0
8
0
0
16
0
0
0
0
0
8
% E
% Phe:
8
8
0
8
0
8
0
0
8
0
0
8
8
8
0
% F
% Gly:
8
0
0
8
39
8
0
0
0
0
8
8
8
0
8
% G
% His:
0
0
8
8
0
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
8
8
0
8
0
0
0
0
0
8
8
0
8
0
0
% I
% Lys:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
24
8
0
16
0
8
8
47
39
8
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
0
% N
% Pro:
8
0
0
0
8
31
39
8
8
0
0
8
0
8
39
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% Q
% Arg:
0
0
16
31
0
0
8
0
0
0
8
0
0
0
8
% R
% Ser:
8
8
31
0
8
16
8
0
8
47
16
16
0
16
8
% S
% Thr:
31
8
0
0
8
0
16
47
47
8
0
8
0
8
0
% T
% Val:
8
8
8
0
0
0
0
0
0
0
0
8
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _