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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK7
All Species:
22.12
Human Site:
Y682
Identified Species:
40.56
UniProt:
Q16549
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16549
NP_004707.2
785
86247
Y682
T
V
F
W
T
V
Y
Y
M
L
E
V
Y
L
S
Chimpanzee
Pan troglodytes
XP_508776
785
86375
Y682
T
V
F
W
T
V
Y
Y
M
L
E
V
Y
L
S
Rhesus Macaque
Macaca mulatta
XP_001093007
786
86480
Y682
T
V
F
W
T
V
Y
Y
M
L
E
V
Y
L
S
Dog
Lupus familis
XP_850224
787
86625
Y682
T
I
F
W
T
V
Y
Y
M
L
E
I
Y
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61139
770
84397
Y680
F
S
V
F
W
T
I
Y
Y
M
L
E
V
C
L
Rat
Rattus norvegicus
Q62849
783
85580
Y681
S
V
F
W
T
I
Y
Y
M
L
E
V
C
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025528
629
69561
P539
V
T
V
T
I
T
H
P
R
R
G
N
L
E
I
Frog
Xenopus laevis
P29119
783
86425
C649
C
H
V
S
C
A
T
C
K
G
T
T
I
N
D
Zebra Danio
Brachydanio rerio
NP_001076494
709
77055
V619
P
C
P
P
G
I
D
V
P
A
E
I
V
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26016
1269
138609
A999
S
G
N
G
S
I
K
A
A
K
Q
V
K
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
Y800
D
L
C
G
D
G
Y
Y
I
N
A
V
G
K
C
Sea Urchin
Strong. purpuratus
XP_789974
1055
115221
L863
A
S
Q
K
N
V
S
L
E
I
Q
A
A
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
T689
T
I
F
L
I
G
A
T
F
L
V
L
Y
F
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.2
91.1
N.A.
85.3
87.3
N.A.
N.A.
63
37.3
59.6
N.A.
25.6
N.A.
29.1
36
Protein Similarity:
100
99.2
98.7
94.9
N.A.
89.5
91.7
N.A.
N.A.
69.5
52.8
70.9
N.A.
37.8
N.A.
43.7
48.5
P-Site Identity:
100
100
100
86.6
N.A.
6.6
80
N.A.
N.A.
0
0
6.6
N.A.
13.3
N.A.
20
13.3
P-Site Similarity:
100
100
100
100
N.A.
20
93.3
N.A.
N.A.
6.6
0
20
N.A.
40
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
8
8
8
8
8
8
8
8
0
% A
% Cys:
8
8
8
0
8
0
0
8
0
0
0
0
8
8
8
% C
% Asp:
8
0
0
0
8
0
8
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
47
8
0
16
0
% E
% Phe:
8
0
47
8
0
0
0
0
8
0
0
0
0
8
0
% F
% Gly:
0
8
0
16
8
16
0
0
0
8
8
0
8
0
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
16
24
8
0
8
8
0
16
8
0
8
% I
% Lys:
0
0
0
8
0
0
8
0
8
8
0
0
8
8
0
% K
% Leu:
0
8
0
8
0
0
0
8
0
47
8
8
8
39
8
% L
% Met:
0
0
0
0
0
0
0
0
39
8
0
0
0
0
8
% M
% Asn:
0
0
8
0
8
0
0
0
0
8
0
8
0
16
0
% N
% Pro:
8
0
8
8
0
0
0
8
8
0
0
0
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
16
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
16
16
0
8
8
0
8
0
0
0
0
0
0
0
54
% S
% Thr:
39
8
0
8
39
16
8
8
0
0
8
8
0
0
0
% T
% Val:
8
31
24
0
0
39
0
8
0
0
8
47
16
0
0
% V
% Trp:
0
0
0
39
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
47
54
8
0
0
0
39
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _