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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL17A
All Species:
12.42
Human Site:
Y108
Identified Species:
34.17
UniProt:
Q16552
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16552
NP_002181.1
155
17504
Y108
N
A
D
G
N
V
D
Y
H
M
N
S
V
P
I
Chimpanzee
Pan troglodytes
XP_527408
155
17456
Y108
N
A
D
G
N
V
D
Y
H
M
N
S
V
P
I
Rhesus Macaque
Macaca mulatta
XP_001106391
155
17514
Y108
N
A
D
G
N
V
D
Y
H
M
N
S
V
P
I
Dog
Lupus familis
XP_538959
157
17585
S109
N
A
E
G
Q
E
D
S
S
M
N
S
V
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q62386
158
17472
H111
N
A
E
G
K
L
D
H
H
M
N
S
V
L
I
Rat
Rattus norvegicus
Q61453
150
16858
H103
N
A
E
G
K
L
D
H
H
M
N
S
V
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509887
166
18387
P119
D
A
Q
K
K
E
D
P
H
M
N
S
L
P
I
Chicken
Gallus gallus
NP_989791
169
18924
H122
N
S
A
G
Q
L
D
H
S
V
N
S
V
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001018634
140
15821
R98
L
P
T
G
V
D
K
R
L
N
S
V
P
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
46.5
N.A.
61.3
60
N.A.
51.8
44.9
N.A.
32.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
97.4
60.5
N.A.
75.3
76.1
N.A.
63.8
65
N.A.
45.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
66.6
66.6
N.A.
53.3
53.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
86.6
86.6
N.A.
66.6
80
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
78
12
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
34
0
0
12
89
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
34
0
0
23
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
89
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
34
67
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
89
% I
% Lys:
0
0
0
12
34
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
0
0
0
34
0
0
12
0
0
0
12
23
0
% L
% Met:
0
0
0
0
0
0
0
0
0
78
0
0
0
0
0
% M
% Asn:
78
0
0
0
34
0
0
0
0
12
89
0
0
0
0
% N
% Pro:
0
12
0
0
0
0
0
12
0
0
0
0
12
67
0
% P
% Gln:
0
0
12
0
23
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
12
0
0
0
0
0
12
23
0
12
89
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
12
34
0
0
0
12
0
12
78
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _