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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYPL1
All Species:
17.27
Human Site:
S245
Identified Species:
42.22
UniProt:
Q16563
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16563
NP_006745.1
259
28565
S245
L
H
S
P
S
N
T
S
A
P
H
S
Q
G
G
Chimpanzee
Pan troglodytes
XP_001162151
259
28561
S245
L
H
S
P
S
N
T
S
A
P
H
S
Q
G
G
Rhesus Macaque
Macaca mulatta
XP_001090107
259
28611
S245
L
H
S
P
S
N
T
S
A
P
H
S
Q
G
G
Dog
Lupus familis
XP_533096
484
53333
S470
L
H
S
P
S
N
T
S
A
S
H
G
Q
G
G
Cat
Felis silvestris
Mouse
Mus musculus
O09117
261
28881
S247
L
H
S
P
S
N
T
S
A
S
H
S
Q
G
G
Rat
Rattus norvegicus
P07825
307
33292
A230
W
A
A
P
F
M
R
A
P
P
G
A
P
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520369
235
26227
A222
S
F
H
N
P
S
N
A
A
T
H
G
S
G
G
Chicken
Gallus gallus
XP_415953
236
25887
R223
N
L
H
S
R
L
I
R
G
S
Q
V
P
G
T
Frog
Xenopus laevis
NP_001085181
231
25765
Q218
T
S
L
H
S
P
P
Q
Q
P
N
P
E
Q
D
Zebra Danio
Brachydanio rerio
NP_997834
232
25788
L219
F
L
Y
K
E
T
P
L
H
R
T
T
N
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.1
45
N.A.
81.6
38.1
N.A.
55.2
54
52.1
45.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98
48.3
N.A.
88.8
52.4
N.A.
67.5
63.7
62.5
58.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
13.3
N.A.
26.6
6.6
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
33.3
N.A.
40
6.6
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
20
60
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
0
10
10
0
% E
% Phe:
10
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
10
20
0
70
60
% G
% His:
0
50
20
10
0
0
0
0
10
0
60
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
50
20
10
0
0
10
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
50
10
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
0
60
10
10
20
0
10
50
0
10
20
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
10
0
10
0
50
20
10
% Q
% Arg:
0
0
0
0
10
0
10
10
0
10
0
0
0
0
0
% R
% Ser:
10
10
50
10
60
10
0
50
0
30
0
40
10
0
0
% S
% Thr:
10
0
0
0
0
10
50
0
0
10
10
10
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _