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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYPL1 All Species: 9.7
Human Site: T77 Identified Species: 23.7
UniProt: Q16563 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16563 NP_006745.1 259 28565 T77 E N K T V T A T F G Y P F R L
Chimpanzee Pan troglodytes XP_001162151 259 28561 T77 E N K T V T A T F G Y P F R L
Rhesus Macaque Macaca mulatta XP_001090107 259 28611 T77 E N K T I T A T F G Y P F R L
Dog Lupus familis XP_533096 484 53333 A302 E N K T I T A A F A Y P F R L
Cat Felis silvestris
Mouse Mus musculus O09117 261 28881 A77 N K N Q T V T A T F G Y P F R
Rat Rattus norvegicus P07825 307 33292 P68 I E V E F E Y P F R L H Q V Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520369 235 26227 F62 D P T C S L F F F R L N H A N
Chicken Gallus gallus XP_415953 236 25887 N65 F A Y P F R L N T V R F S A P
Frog Xenopus laevis NP_001085181 231 25765 F60 A A S F M Y P F R L N V Q T F
Zebra Danio Brachydanio rerio NP_997834 232 25788 Y61 E I N A S F S Y P F R L N T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 96.1 45 N.A. 81.6 38.1 N.A. 55.2 54 52.1 45.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 98 48.3 N.A. 88.8 52.4 N.A. 67.5 63.7 62.5 58.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 80 N.A. 0 6.6 N.A. 6.6 0 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 0 6.6 N.A. 13.3 0 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 20 0 10 0 0 40 20 0 10 0 0 0 20 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 50 10 0 10 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 10 20 10 10 20 60 20 0 10 40 10 10 % F
% Gly: 0 0 0 0 0 0 0 0 0 30 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % H
% Ile: 10 10 0 0 20 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 40 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 10 0 0 10 20 10 0 0 40 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 40 20 0 0 0 0 10 0 0 10 10 10 0 10 % N
% Pro: 0 10 0 10 0 0 10 10 10 0 0 40 10 0 10 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 20 0 10 % Q
% Arg: 0 0 0 0 0 10 0 0 10 20 20 0 0 40 10 % R
% Ser: 0 0 10 0 20 0 10 0 0 0 0 0 10 0 0 % S
% Thr: 0 0 10 40 10 40 10 30 20 0 0 0 0 20 0 % T
% Val: 0 0 10 0 20 10 0 0 0 10 0 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 10 10 10 0 0 40 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _