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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAMK4 All Species: 9.7
Human Site: S37 Identified Species: 17.78
UniProt: Q16566 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16566 NP_001735.1 473 51926 S37 P D Y W I D G S N R D A L S D
Chimpanzee Pan troglodytes XP_517873 603 65471 S167 P D Y W I D G S N R D A L S D
Rhesus Macaque Macaca mulatta XP_001101268 613 65896 S177 P D Y W I D G S N R D A L S D
Dog Lupus familis XP_541780 370 41140 V25 D I Y D F R D V L G T G A F S
Cat Felis silvestris
Mouse Mus musculus P08414 469 52609 P37 I D G S N R D P L G D F F E V
Rat Rattus norvegicus P13234 474 53133 P37 I D G S K R D P L S D F F E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513096 402 44436 T37 I D G S N K D T L A H Y F E V
Chicken Gallus gallus Q5ZKI0 479 54184 R53 N T K K L S A R D H Q K L E R
Frog Xenopus laevis Q9DG02 475 53914 R52 N T K K L S A R D H Q K L E R
Zebra Danio Brachydanio rerio NP_001017607 364 40603 G19 A P E Y W I D G S K K E T L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00168 530 59901 H77 H P N I V R L H D S I Q E E N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797065 374 40935 M29 L G A G A G G M K V S H I A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZSA2 531 59876 R77 G K P F E D I R K F Y S L G K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.2 73.2 34 N.A. 80.3 79.9 N.A. 70.1 34.4 33.6 65.3 N.A. 30.3 N.A. N.A. 40.3
Protein Similarity: 100 78.4 74.8 49.6 N.A. 85.6 86.5 N.A. 78 53.8 52.2 72.3 N.A. 49.8 N.A. N.A. 56.2
P-Site Identity: 100 100 100 6.6 N.A. 13.3 13.3 N.A. 6.6 6.6 6.6 0 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 6.6 N.A. 13.3 13.3 N.A. 13.3 20 20 20 N.A. 20 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 32.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 8 0 16 0 0 8 0 24 8 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 47 0 8 0 31 39 0 24 0 39 0 0 0 24 % D
% Glu: 0 0 8 0 8 0 0 0 0 0 0 8 8 47 8 % E
% Phe: 0 0 0 8 8 0 0 0 0 8 0 16 24 8 0 % F
% Gly: 8 8 24 8 0 8 31 8 0 16 0 8 0 8 0 % G
% His: 8 0 0 0 0 0 0 8 0 16 8 8 0 0 0 % H
% Ile: 24 8 0 8 24 8 8 0 0 0 8 0 8 0 0 % I
% Lys: 0 8 16 16 8 8 0 0 16 8 8 16 0 0 8 % K
% Leu: 8 0 0 0 16 0 8 0 31 0 0 0 47 8 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 16 0 8 0 16 0 0 0 24 0 0 0 0 0 8 % N
% Pro: 24 16 8 0 0 0 0 16 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 16 8 0 0 0 % Q
% Arg: 0 0 0 0 0 31 0 24 0 24 0 0 0 0 16 % R
% Ser: 0 0 0 24 0 16 0 24 8 16 8 8 0 24 8 % S
% Thr: 0 16 0 0 0 0 0 8 0 0 8 0 8 0 0 % T
% Val: 0 0 0 0 8 0 0 8 0 8 0 0 0 0 24 % V
% Trp: 0 0 0 24 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 31 8 0 0 0 0 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _