KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DARC
All Species:
4.55
Human Site:
S17
Identified Species:
20
UniProt:
Q16570
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16570
NP_001116423.1
336
35553
S17
L
S
P
S
T
E
N
S
S
Q
L
D
F
E
D
Chimpanzee
Pan troglodytes
Q95LF3
336
35607
S17
L
S
P
S
T
E
N
S
S
Q
L
D
F
E
D
Rhesus Macaque
Macaca mulatta
Q95LF2
335
35359
N16
E
L
S
P
S
T
Q
N
S
S
Q
L
N
S
D
Dog
Lupus familis
XP_536127
432
46661
E113
L
Q
Q
Q
A
A
D
E
A
S
T
D
L
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUI6
334
36675
K15
V
E
T
L
S
L
D
K
N
G
T
Q
F
T
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026162
377
42643
Q14
S
L
L
A
G
G
K
Q
E
D
L
L
A
D
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
91.6
50.6
N.A.
60.4
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
94.9
59.4
N.A.
72.9
N.A.
N.A.
N.A.
40.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
13.3
N.A.
6.6
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
26.6
N.A.
33.3
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
17
17
0
0
17
0
0
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
34
0
0
17
0
50
0
17
50
% D
% Glu:
17
17
0
0
0
34
0
17
17
0
0
0
0
34
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
50
% F
% Gly:
0
0
0
0
17
17
0
0
0
17
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% I
% Lys:
0
0
0
0
0
0
17
17
0
0
0
0
0
0
0
% K
% Leu:
50
34
17
17
0
17
0
0
0
0
50
34
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
34
17
17
0
0
0
17
0
0
% N
% Pro:
0
0
34
17
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
17
17
0
0
17
17
0
34
17
17
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
34
17
34
34
0
0
34
50
34
0
0
0
17
0
% S
% Thr:
0
0
17
0
34
17
0
0
0
0
34
0
0
17
0
% T
% Val:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _