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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF74 All Species: 10.91
Human Site: S39 Identified Species: 40
UniProt: Q16587 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16587 NP_003417.2 644 72207 S39 W G L P E A R S K E S V S F K
Chimpanzee Pan troglodytes XP_530361 644 72192 S39 W G L P E A R S K E S V S F K
Rhesus Macaque Macaca mulatta XP_001082863 644 71474 S39 W G L P E A R S K E S V S F K
Dog Lupus familis XP_543555 991 112953 T97 D Q E T R S R T A K S N L K Q
Cat Felis silvestris
Mouse Mus musculus Q7TSH9 737 84009 K43 N F T Q E E W K H L D P I Q R
Rat Rattus norvegicus Q9EPU7 560 64174 L38 L D P A Q R T L Y R E V M L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519206 536 61490 R17 D V A V T F T R A E W E H L D
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 90.5 44 N.A. 40.5 39.2 N.A. 39.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 91.9 53.5 N.A. 54.6 55.2 N.A. 54.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 6.6 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 40 N.A. 13.3 20 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 15 0 43 0 0 29 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 29 15 0 0 0 0 0 0 0 0 15 0 0 0 15 % D
% Glu: 0 0 15 0 58 15 0 0 0 58 15 15 0 0 15 % E
% Phe: 0 15 0 0 0 15 0 0 0 0 0 0 0 43 0 % F
% Gly: 0 43 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 15 0 0 0 15 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % I
% Lys: 0 0 0 0 0 0 0 15 43 15 0 0 0 15 43 % K
% Leu: 15 0 43 0 0 0 0 15 0 15 0 0 15 29 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % M
% Asn: 15 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % N
% Pro: 0 0 15 43 0 0 0 0 0 0 0 15 0 0 0 % P
% Gln: 0 15 0 15 15 0 0 0 0 0 0 0 0 15 15 % Q
% Arg: 0 0 0 0 15 15 58 15 0 15 0 0 0 0 15 % R
% Ser: 0 0 0 0 0 15 0 43 0 0 58 0 43 0 0 % S
% Thr: 0 0 15 15 15 0 29 15 0 0 0 0 0 0 0 % T
% Val: 0 15 0 15 0 0 0 0 0 0 0 58 0 0 0 % V
% Trp: 43 0 0 0 0 0 15 0 0 0 15 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _