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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FXN
All Species:
24.85
Human Site:
S161
Identified Species:
42.05
UniProt:
Q16595
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16595
NP_000135.2
210
23135
S161
I
W
L
S
S
P
S
S
G
P
K
R
Y
D
W
Chimpanzee
Pan troglodytes
XP_001137864
210
23069
S161
I
W
L
S
S
P
S
S
G
P
K
R
Y
D
W
Rhesus Macaque
Macaca mulatta
XP_001093449
210
23092
S161
I
W
L
S
S
P
S
S
G
P
K
R
Y
D
W
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O35943
207
22905
S158
I
W
L
S
S
P
S
S
G
P
K
R
Y
D
W
Rat
Rattus norvegicus
XP_001078791
208
23008
S159
I
W
L
S
S
P
S
S
G
P
K
R
Y
D
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505861
288
30735
S239
I
W
L
S
S
P
S
S
G
P
K
R
Y
D
W
Chicken
Gallus gallus
XP_424827
144
16168
P96
L
S
S
P
T
S
G
P
K
R
Y
D
W
T
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001076485
169
18984
S120
P
N
R
Q
I
W
L
S
S
P
T
S
G
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W385
190
20903
K142
S
S
P
T
S
G
P
K
R
Y
D
F
V
G
T
Honey Bee
Apis mellifera
XP_625012
206
23630
P157
R
Q
I
W
L
S
S
P
K
S
G
P
K
R
Y
Nematode Worm
Caenorhab. elegans
Q9TY03
136
15700
S88
N
K
Q
I
W
L
S
S
P
M
S
G
P
K
R
Sea Urchin
Strong. purpuratus
XP_001204076
163
18316
T115
Q
I
W
L
S
S
P
T
S
G
P
K
R
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZR07
187
21412
W139
Q
T
P
N
R
Q
I
W
M
S
S
P
V
S
G
Baker's Yeast
Sacchar. cerevisiae
Q07540
174
19472
P126
Y
V
I
N
K
Q
P
P
N
K
Q
I
W
L
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
92.3
N.A.
N.A.
71.9
72.8
N.A.
52.4
55.2
N.A.
45.2
N.A.
37.1
31.4
32.3
39
Protein Similarity:
100
95.7
93.8
N.A.
N.A.
77.1
79.5
N.A.
58.6
61.4
N.A.
57.6
N.A.
55.7
50.4
42.3
52.3
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
0
N.A.
13.3
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
20
N.A.
13.3
N.A.
13.3
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
30.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.6
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
8
0
43
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
8
8
0
43
8
8
8
8
8
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
43
8
15
8
8
0
8
0
0
0
0
8
0
0
0
% I
% Lys:
0
8
0
0
8
0
0
8
15
8
43
8
8
8
8
% K
% Leu:
8
0
43
8
8
8
8
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
8
8
0
15
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
8
0
15
8
0
43
22
22
8
50
8
15
8
8
0
% P
% Gln:
15
8
8
8
0
15
0
0
0
0
8
0
0
0
0
% Q
% Arg:
8
0
8
0
8
0
0
0
8
8
0
43
8
8
8
% R
% Ser:
8
15
8
43
58
22
58
58
15
15
15
8
0
8
0
% S
% Thr:
0
8
0
8
8
0
0
8
0
0
8
0
0
8
8
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
15
0
0
% V
% Trp:
0
43
8
8
8
8
0
8
0
0
0
0
15
0
43
% W
% Tyr:
8
0
0
0
0
0
0
0
0
8
8
0
43
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _