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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FXN
All Species:
22.73
Human Site:
T119
Identified Species:
38.46
UniProt:
Q16595
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16595
NP_000135.2
210
23135
T119
D
L
A
D
K
P
Y
T
F
E
D
Y
D
V
S
Chimpanzee
Pan troglodytes
XP_001137864
210
23069
T119
D
L
A
D
K
P
Y
T
F
E
D
Y
D
V
S
Rhesus Macaque
Macaca mulatta
XP_001093449
210
23092
T119
D
L
A
D
K
P
Y
T
F
E
D
Y
D
V
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O35943
207
22905
T116
D
L
A
D
K
P
Y
T
L
E
D
Y
D
V
S
Rat
Rattus norvegicus
XP_001078791
208
23008
T117
D
L
A
D
K
P
Y
T
L
K
D
Y
D
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505861
288
30735
T197
D
L
A
D
K
P
Y
T
S
E
D
F
D
V
S
Chicken
Gallus gallus
XP_424827
144
16168
E54
T
D
K
P
F
T
P
E
D
Y
D
V
S
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001076485
169
18984
D78
D
Y
F
E
D
L
T
D
E
N
F
T
G
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W385
190
20903
G100
E
N
A
S
E
L
Q
G
T
D
V
A
Y
S
D
Honey Bee
Apis mellifera
XP_625012
206
23630
A115
F
D
E
L
V
E
Q
A
I
H
L
S
D
A
D
Nematode Worm
Caenorhab. elegans
Q9TY03
136
15700
S46
Y
F
D
Q
I
A
D
S
F
P
V
S
E
Q
F
Sea Urchin
Strong. purpuratus
XP_001204076
163
18316
K73
E
I
L
G
D
S
E
K
C
P
A
D
F
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZR07
187
21412
E97
N
H
L
L
E
K
I
E
D
Y
G
D
N
V
Q
Baker's Yeast
Sacchar. cerevisiae
Q07540
174
19472
L84
A
D
D
Y
L
D
H
L
L
D
S
L
E
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
92.3
N.A.
N.A.
71.9
72.8
N.A.
52.4
55.2
N.A.
45.2
N.A.
37.1
31.4
32.3
39
Protein Similarity:
100
95.7
93.8
N.A.
N.A.
77.1
79.5
N.A.
58.6
61.4
N.A.
57.6
N.A.
55.7
50.4
42.3
52.3
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
86.6
N.A.
86.6
6.6
N.A.
6.6
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
93.3
13.3
N.A.
20
N.A.
26.6
6.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
30.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.6
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
50
0
0
8
0
8
0
0
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
50
22
15
43
15
8
8
8
15
15
50
15
50
8
22
% D
% Glu:
15
0
8
8
15
8
8
15
8
36
0
0
15
8
0
% E
% Phe:
8
8
8
0
8
0
0
0
29
0
8
8
8
0
8
% F
% Gly:
0
0
0
8
0
0
0
8
0
0
8
0
8
0
8
% G
% His:
0
8
0
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
8
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
43
8
0
8
0
8
0
0
0
0
0
% K
% Leu:
0
43
15
15
8
15
0
8
22
0
8
8
0
15
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
8
0
43
8
0
0
15
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
15
0
0
0
0
0
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
8
0
8
8
0
8
15
8
8
43
% S
% Thr:
8
0
0
0
0
8
8
43
8
0
0
8
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
15
8
0
50
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
8
0
0
43
0
0
15
0
36
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _