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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFE2
All Species:
22.73
Human Site:
S149
Identified Species:
55.56
UniProt:
Q16621
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16621
NP_001129495.1
373
41473
S149
P
E
S
D
S
G
L
S
L
N
Y
S
D
A
E
Chimpanzee
Pan troglodytes
XP_001170837
373
41424
S149
P
E
S
D
S
G
L
S
L
N
Y
S
D
A
E
Rhesus Macaque
Macaca mulatta
XP_001109451
373
41470
S149
P
E
S
D
S
G
L
S
L
N
Y
S
D
A
E
Dog
Lupus familis
XP_543621
373
41136
S149
P
E
S
D
S
G
L
S
L
N
Y
S
D
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q07279
373
41546
S149
P
E
S
D
S
G
L
S
L
N
Y
S
D
A
E
Rat
Rattus norvegicus
Q6AYT2
373
41477
S149
P
E
S
D
S
G
L
S
L
N
Y
S
D
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514024
136
15506
Chicken
Gallus gallus
Q5ZL67
772
85168
E537
S
E
N
V
D
F
E
E
A
E
G
A
V
G
Y
Frog
Xenopus laevis
NP_001088660
343
38204
L137
S
T
N
S
V
R
Q
L
C
K
G
Q
D
E
F
Zebra Danio
Brachydanio rerio
NP_878309
586
65869
E361
G
F
S
D
S
D
S
E
E
M
E
G
S
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.8
92.2
N.A.
89
90
N.A.
28.9
24.2
32.4
30.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.6
94
N.A.
91.9
92.4
N.A.
31.8
34.5
49
43.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
6.6
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
20
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
10
0
60
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
70
10
10
0
0
0
0
0
0
70
0
0
% D
% Glu:
0
70
0
0
0
0
10
20
10
10
10
0
0
10
60
% E
% Phe:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
0
0
0
0
60
0
0
0
0
20
10
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
60
10
60
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
20
0
0
0
0
0
0
60
0
0
0
0
0
% N
% Pro:
60
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
0
70
10
70
0
10
60
0
0
0
60
10
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
10
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _