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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX1A
All Species:
49.39
Human Site:
S208
Identified Species:
83.59
UniProt:
Q16623
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16623
NP_004594.1
288
33023
S208
E
I
I
K
L
E
N
S
I
R
E
L
H
D
M
Chimpanzee
Pan troglodytes
XP_001146754
288
33051
S208
E
I
I
K
L
E
N
S
I
R
E
L
H
D
M
Rhesus Macaque
Macaca mulatta
NP_001028037
288
32987
S208
E
I
I
K
L
E
N
S
I
R
E
L
H
D
M
Dog
Lupus familis
XP_849756
293
33456
S213
E
I
I
K
L
E
N
S
I
R
E
L
H
D
M
Cat
Felis silvestris
Mouse
Mus musculus
O35526
288
33036
S208
E
I
I
K
L
E
T
S
I
R
E
L
H
D
M
Rat
Rattus norvegicus
P32851
288
33049
S208
E
I
I
K
L
E
N
S
I
R
E
L
H
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233551
316
35842
S236
E
I
I
K
L
E
N
S
I
R
E
L
H
D
M
Frog
Xenopus laevis
NP_001086322
286
32704
S206
D
I
V
R
L
E
S
S
L
K
E
L
H
D
M
Zebra Danio
Brachydanio rerio
NP_571598
288
33347
S207
E
I
I
K
L
E
N
S
I
R
E
L
H
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
S211
D
I
M
K
L
E
T
S
I
K
E
L
H
D
M
Honey Bee
Apis mellifera
XP_393760
291
33455
S212
D
I
I
K
L
E
N
S
I
R
E
L
H
D
M
Nematode Worm
Caenorhab. elegans
O16000
291
33234
S209
D
I
M
K
L
E
S
S
I
R
E
L
H
D
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRV7
306
34701
E219
H
D
A
V
R
D
L
E
K
K
L
L
D
L
Q
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
L207
R
H
Q
E
L
L
K
L
E
K
T
M
A
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
98.9
93.1
N.A.
98.2
98.6
N.A.
N.A.
85.7
67.3
82.9
N.A.
70
69.4
63.2
N.A.
Protein Similarity:
100
95.4
98.9
94.5
N.A.
98.9
99.3
N.A.
N.A.
89.8
85.7
93.4
N.A.
83.1
81.4
80
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
100
60
100
N.A.
73.3
93.3
80
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
100
100
100
N.A.
93.3
100
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.3
47.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
8
0
0
0
8
0
0
0
0
0
0
8
86
0
% D
% Glu:
58
0
0
8
0
86
0
8
8
0
86
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
8
0
0
0
0
0
0
0
0
0
0
86
0
0
% H
% Ile:
0
86
65
0
0
0
0
0
79
0
0
0
0
0
0
% I
% Lys:
0
0
0
79
0
0
8
0
8
29
0
0
0
0
0
% K
% Leu:
0
0
0
0
93
8
8
8
8
0
8
93
0
8
8
% L
% Met:
0
0
15
0
0
0
0
0
0
0
0
8
0
0
86
% M
% Asn:
0
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
0
0
8
8
0
0
0
0
72
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
15
86
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
15
0
0
0
8
0
0
0
0
% T
% Val:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _