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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX1A All Species: 23.94
Human Site: T10 Identified Species: 40.51
UniProt: Q16623 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16623 NP_004594.1 288 33023 T10 D R T Q E L R T A K D S D D D
Chimpanzee Pan troglodytes XP_001146754 288 33051 T10 D R T Q E L R T A K D S D D D
Rhesus Macaque Macaca mulatta NP_001028037 288 32987 T10 D R T Q E L R T A K D S D D D
Dog Lupus familis XP_849756 293 33456 Q15 A H S R D S K Q A K D S D D D
Cat Felis silvestris
Mouse Mus musculus O35526 288 33036 T10 D R T Q E L R T A K D S D D D
Rat Rattus norvegicus P32851 288 33049 T10 D R T Q E L R T A K D S D D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233551 316 35842 K38 E P S G F T P K A K D S D D D
Frog Xenopus laevis NP_001086322 286 32704 A10 D R L E Q L K A T R D T D D Q
Zebra Danio Brachydanio rerio NP_571598 288 33347 S10 D R T Q E L R S A K D S D D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24547 291 33630 H10 K D R L A A L H A A Q S D D E
Honey Bee Apis mellifera XP_393760 291 33455 A11 D R L A A L V A A Q S D D D D
Nematode Worm Caenorhab. elegans O16000 291 33234 A11 D R L S A L K A A Q S E D E Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRV7 306 34701 S23 S N R S D I E S G H G P G N S
Baker's Yeast Sacchar. cerevisiae P39926 295 33715 E18 N P Y A E N Y E M Q E D L N N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93 98.9 93.1 N.A. 98.2 98.6 N.A. N.A. 85.7 67.3 82.9 N.A. 70 69.4 63.2 N.A.
Protein Similarity: 100 95.4 98.9 94.5 N.A. 98.9 99.3 N.A. N.A. 89.8 85.7 93.4 N.A. 83.1 81.4 80 N.A.
P-Site Identity: 100 100 100 46.6 N.A. 100 100 N.A. N.A. 46.6 40 93.3 N.A. 26.6 46.6 33.3 N.A.
P-Site Similarity: 100 100 100 73.3 N.A. 100 100 N.A. N.A. 60 73.3 100 N.A. 33.3 53.3 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.2 24.4 N.A.
Protein Similarity: N.A. N.A. N.A. 51.3 47.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 15 22 8 0 22 79 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 65 8 0 0 15 0 0 0 0 0 65 15 86 79 65 % D
% Glu: 8 0 0 8 50 0 8 8 0 0 8 8 0 8 8 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 8 0 8 0 8 0 0 % G
% His: 0 8 0 0 0 0 0 8 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 22 8 0 58 0 0 0 0 0 % K
% Leu: 0 0 22 8 0 65 8 0 0 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 8 8 0 0 0 8 0 0 0 0 0 0 0 15 8 % N
% Pro: 0 15 0 0 0 0 8 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 43 8 0 0 8 0 22 8 0 0 0 15 % Q
% Arg: 0 65 15 8 0 0 43 0 0 8 0 0 0 0 0 % R
% Ser: 8 0 15 15 0 8 0 15 0 0 15 65 0 0 8 % S
% Thr: 0 0 43 0 0 8 0 36 8 0 0 8 0 0 0 % T
% Val: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _