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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEA1 All Species: 5.15
Human Site: S69 Identified Species: 16.19
UniProt: Q16626 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.43
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16626 NP_055438.1 185 19905 S69 G S G P A G Y S Y Q P L N Q D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001087765 162 17548 V70 A P V G D G D V V A D I Q D R
Dog Lupus familis XP_532141 174 18635 D80 A P V G D G E D V V A D I Q D
Cat Felis silvestris
Mouse Mus musculus Q64327 174 18566 D80 A P V G E G E D G A A D I Q D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508617 179 19163 S69 Q G G P A G Y S Y Q P L T Q D
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002664133 185 20494 P77 V N G S H T E P A D E G T T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624684 152 17051 E69 E W I T N V G E S S Q V L R A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001184523 192 20538 S78 P H A H S Q Y S E T C T S S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 87 88.1 N.A. 88.1 N.A. N.A. 66.4 N.A. N.A. 44.3 N.A. N.A. 23.7 N.A. 20.3
Protein Similarity: 100 N.A. 87 91.8 N.A. 91.3 N.A. N.A. 74 N.A. N.A. 62.1 N.A. N.A. 43.2 N.A. 33.8
P-Site Identity: 100 N.A. 6.6 20 N.A. 20 N.A. N.A. 80 N.A. N.A. 6.6 N.A. N.A. 0 N.A. 20
P-Site Similarity: 100 N.A. 13.3 20 N.A. 20 N.A. N.A. 80 N.A. N.A. 13.3 N.A. N.A. 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 38 0 13 0 25 0 0 0 13 25 25 0 0 0 25 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % C
% Asp: 0 0 0 0 25 0 13 25 0 13 13 25 0 13 63 % D
% Glu: 13 0 0 0 13 0 38 13 13 0 13 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 13 13 38 38 0 63 13 0 13 0 0 13 0 0 0 % G
% His: 0 13 0 13 13 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 13 0 0 0 0 0 0 0 0 13 25 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 25 13 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 13 0 0 13 0 0 0 0 0 0 0 13 0 0 % N
% Pro: 13 38 0 25 0 0 0 13 0 0 25 0 0 0 0 % P
% Gln: 13 0 0 0 0 13 0 0 0 25 13 0 13 50 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 13 % R
% Ser: 0 13 0 13 13 0 0 38 13 13 0 0 13 13 0 % S
% Thr: 0 0 0 13 0 13 0 0 0 13 0 13 25 13 0 % T
% Val: 13 0 38 0 0 13 0 13 25 13 0 13 0 0 0 % V
% Trp: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 38 0 25 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _