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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS7 All Species: 27.58
Human Site: S175 Identified Species: 43.33
UniProt: Q16629 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16629 NP_001026854.1 238 27367 S175 L R R S R S A S L R R S R S G
Chimpanzee Pan troglodytes Q5R1W5 221 25469 R154 S K S R S R T R S R S R S T S
Rhesus Macaque Macaca mulatta XP_001102729 329 37353 S266 L R R S R S A S L R R S R S G
Dog Lupus familis XP_532939 238 27361 S175 L R R S R S A S L R R S R S G
Cat Felis silvestris
Mouse Mus musculus Q8BL97 267 30799 S204 L R R S R S A S L R R S R S G
Rat Rattus norvegicus Q09167 269 30873 S197 R S R T R S S S R S R S R S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506905 228 26306 S165 P R R S R S A S P R R S R S G
Chicken Gallus gallus P30352 221 25506 R154 S K S R S R T R S R S R S T S
Frog Xenopus laevis NP_001086749 234 26928 R172 S A S P R R S R S A T P R R S
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 E183 N T K F R S H E G E T A Y I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02427 144 15994 S82 T R I R V E M S S G R S R D R
Honey Bee Apis mellifera XP_001122800 206 24203 S143 Y S R S K S Q S R S R S R S R
Nematode Worm Caenorhab. elegans Q18409 179 20463 R117 S R S R D R G R D R S R D R S
Sea Urchin Strong. purpuratus XP_789638 215 22776 R153 R G G R G P P R G D S K C Y E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 S221 R S R S R G R S V S R S R S R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.2 72.3 98.3 N.A. 86.5 37.1 N.A. 92 46.2 89.5 34.6 N.A. 36.1 54.2 47.9 27.3
Protein Similarity: 100 55.4 72.3 99.5 N.A. 87.6 49.4 N.A. 93.6 55.4 92 43.2 N.A. 47 65.9 51.6 35.2
P-Site Identity: 100 6.6 100 100 N.A. 100 53.3 N.A. 86.6 6.6 13.3 13.3 N.A. 33.3 53.3 13.3 0
P-Site Similarity: 100 20 100 100 N.A. 100 66.6 N.A. 86.6 20 20 26.6 N.A. 33.3 60 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. 39.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 34 0 0 7 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 0 0 0 7 0 0 0 7 7 0 0 7 7 0 % D
% Glu: 0 0 0 0 0 7 0 7 0 7 0 0 0 0 7 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 7 0 7 7 7 0 14 7 0 0 0 0 34 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % I
% Lys: 0 14 7 0 7 0 0 0 0 0 0 7 0 0 0 % K
% Leu: 27 0 0 0 0 0 0 0 27 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 0 0 7 0 7 7 0 7 0 0 7 0 0 0 % P
% Gln: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Q
% Arg: 20 47 54 34 60 27 7 34 14 54 60 20 67 14 34 % R
% Ser: 27 20 27 47 14 54 14 60 27 20 27 60 14 54 27 % S
% Thr: 7 7 0 7 0 0 14 0 0 0 14 0 0 14 0 % T
% Val: 0 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _