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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS7 All Species: 31.21
Human Site: S227 Identified Species: 49.05
UniProt: Q16629 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16629 NP_001026854.1 238 27367 S227 R S R S P S G S P R R S A S P
Chimpanzee Pan troglodytes Q5R1W5 221 25469 S206 E P K S R S R S K S P P E S P
Rhesus Macaque Macaca mulatta XP_001102729 329 37353 S318 R S R S P S G S P R R S A S P
Dog Lupus familis XP_532939 238 27361 S227 R S R S P S G S P R R S A S P
Cat Felis silvestris
Mouse Mus musculus Q8BL97 267 30799 S256 R S R S P S G S P H R S A S P
Rat Rattus norvegicus Q09167 269 30873 A249 S S R S K S P A S V D R Q R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506905 228 26306 S217 R S R S P S G S P R R S A S P
Chicken Gallus gallus P30352 221 25506 S206 E S N S R S R S K S P P K S P
Frog Xenopus laevis NP_001086749 234 26928 P224 S R S P S R S P R R S L S P E
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 S235 S R G S P R Y S P R H S R S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02427 144 15994 Q134 L Q Q Q P S S Q P Q P A T F N
Honey Bee Apis mellifera XP_001122800 206 24203 T195 R D R S P R R T K S K S V S R
Nematode Worm Caenorhab. elegans Q18409 179 20463 S169 K S R S R S R S R S R S R S A
Sea Urchin Strong. purpuratus XP_789638 215 22776 G205 R S P A P K R G G Y S R S R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 S273 R S R S R S R S P L P S V Q K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.2 72.3 98.3 N.A. 86.5 37.1 N.A. 92 46.2 89.5 34.6 N.A. 36.1 54.2 47.9 27.3
Protein Similarity: 100 55.4 72.3 99.5 N.A. 87.6 49.4 N.A. 93.6 55.4 92 43.2 N.A. 47 65.9 51.6 35.2
P-Site Identity: 100 33.3 100 100 N.A. 93.3 26.6 N.A. 100 40 6.6 46.6 N.A. 20 40 53.3 20
P-Site Similarity: 100 40 100 100 N.A. 93.3 33.3 N.A. 100 40 13.3 46.6 N.A. 40 53.3 60 33.3
Percent
Protein Identity: N.A. N.A. N.A. 39.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 0 7 0 0 0 7 34 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % D
% Glu: 14 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 7 0 0 0 34 7 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 0 7 0 7 7 0 0 20 0 7 0 7 0 7 % K
% Leu: 7 0 0 0 0 0 0 0 0 7 0 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 0 7 7 7 60 0 7 7 54 0 27 14 0 7 47 % P
% Gln: 0 7 7 7 0 0 0 7 0 7 0 0 7 7 0 % Q
% Arg: 54 14 60 0 27 20 40 0 14 40 40 14 14 14 14 % R
% Ser: 20 67 7 80 7 74 14 67 7 27 14 60 14 67 14 % S
% Thr: 0 0 0 0 0 0 0 7 0 0 0 0 7 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 7 0 0 14 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _