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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS7 All Species: 22.73
Human Site: Y189 Identified Species: 35.71
UniProt: Q16629 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16629 NP_001026854.1 238 27367 Y189 G S I K G S R Y F Q S P S R S
Chimpanzee Pan troglodytes Q5R1W5 221 25469 R168 S K S R S A R R S K S K S S S
Rhesus Macaque Macaca mulatta XP_001102729 329 37353 Y280 G S I K G S R Y F Q S P S R S
Dog Lupus familis XP_532939 238 27361 Y189 G S I K G S R Y F Q S R S R S
Cat Felis silvestris
Mouse Mus musculus Q8BL97 267 30799 Y218 G S I I G S R Y F Q S R S R S
Rat Rattus norvegicus Q09167 269 30873 Y211 R S R R S K S Y S R S R S R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506905 228 26306 Y179 G S L K R S R Y F E S R S R S
Chicken Gallus gallus P30352 221 25506 R168 S K S R S A R R S K S K S S S
Frog Xenopus laevis NP_001086749 234 26928 R186 S R S G S V K R S R S R S R S
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 R197 R V K V D G P R S P S Y G R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02427 144 15994 S96 R R R G E G G S S G R S G S G
Honey Bee Apis mellifera XP_001122800 206 24203 S157 R S K S R S R S K H S R S S S
Nematode Worm Caenorhab. elegans Q18409 179 20463 R131 S R D R S R D R S R D R S R E
Sea Urchin Strong. purpuratus XP_789638 215 22776 F167 E C G E I G H F A R D C N R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 S235 R S R S R S R S P K A K S S R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.2 72.3 98.3 N.A. 86.5 37.1 N.A. 92 46.2 89.5 34.6 N.A. 36.1 54.2 47.9 27.3
Protein Similarity: 100 55.4 72.3 99.5 N.A. 87.6 49.4 N.A. 93.6 55.4 92 43.2 N.A. 47 65.9 51.6 35.2
P-Site Identity: 100 26.6 100 93.3 N.A. 86.6 40 N.A. 73.3 26.6 26.6 20 N.A. 0 40 13.3 6.6
P-Site Similarity: 100 46.6 100 93.3 N.A. 86.6 53.3 N.A. 86.6 46.6 40 20 N.A. 0 40 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. 39.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 14 0 0 7 0 7 0 0 0 0 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 7 0 7 0 7 0 0 0 14 0 0 0 0 % D
% Glu: 7 0 0 7 7 0 0 0 0 7 0 0 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 7 34 0 0 0 0 0 0 % F
% Gly: 34 0 7 14 27 20 7 0 0 7 0 0 14 0 7 % G
% His: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 27 7 7 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 14 14 27 0 7 7 0 7 20 0 20 0 0 7 % K
% Leu: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 7 0 7 7 0 14 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 27 0 0 0 0 0 % Q
% Arg: 34 20 20 27 20 7 60 34 0 27 7 47 0 67 7 % R
% Ser: 27 54 20 14 34 47 7 20 47 0 74 7 80 34 74 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 7 0 7 0 7 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 40 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _