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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF6
All Species:
17.88
Human Site:
S368
Identified Species:
35.76
UniProt:
Q16630
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16630
NP_008938.2
551
59210
S368
F
F
P
P
P
T
N
S
G
M
P
T
S
D
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117360
588
63452
S405
F
F
P
P
P
T
N
S
G
M
P
T
S
D
S
Dog
Lupus familis
XP_531671
611
65331
S428
F
F
P
P
P
T
N
S
G
M
P
T
S
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6NVF9
551
59134
S368
F
F
P
P
P
T
N
S
G
M
P
T
S
D
S
Rat
Rattus norvegicus
Q5XI29
462
51054
L282
A
I
P
P
A
L
H
L
N
P
A
F
F
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL34
551
59341
S368
F
F
P
P
P
A
N
S
G
I
P
T
S
D
S
Frog
Xenopus laevis
Q6DDW4
548
59387
A364
F
F
P
P
P
G
N
A
G
M
T
S
S
D
S
Zebra Danio
Brachydanio rerio
Q6NWC6
545
58757
P361
N
P
A
F
F
P
P
P
G
N
N
M
P
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSH4
652
71076
N402
M
P
P
Q
Q
G
M
N
M
T
P
Q
H
G
P
Honey Bee
Apis mellifera
XP_624359
752
82027
G538
P
P
H
G
P
P
H
G
P
P
H
G
Q
P
H
Nematode Worm
Caenorhab. elegans
NP_501551
489
53643
M306
R
P
M
M
Q
T
S
M
G
I
Q
P
M
M
G
Sea Urchin
Strong. purpuratus
XP_782654
898
96357
P701
P
Q
V
Q
Q
Q
Q
P
Q
Q
A
P
P
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.7
87.8
N.A.
99.6
44.8
N.A.
N.A.
96.7
88.3
84.3
N.A.
42.3
41.3
31.7
33.3
Protein Similarity:
100
N.A.
93.7
88.7
N.A.
99.8
57.1
N.A.
N.A.
97.6
93.2
90.1
N.A.
53.2
49.4
45.9
41.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
N.A.
86.6
73.3
13.3
N.A.
13.3
6.6
13.3
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
20
N.A.
N.A.
93.3
86.6
13.3
N.A.
20
13.3
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
9
9
0
9
0
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
50
50
0
9
9
0
0
0
0
0
0
9
9
0
0
% F
% Gly:
0
0
0
9
0
17
0
9
67
0
0
9
0
9
9
% G
% His:
0
0
9
0
0
0
17
0
0
0
9
0
9
0
9
% H
% Ile:
0
9
0
0
0
0
0
0
0
17
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% L
% Met:
9
0
9
9
0
0
9
9
9
42
0
9
9
9
0
% M
% Asn:
9
0
0
0
0
0
50
9
9
9
9
0
0
0
0
% N
% Pro:
17
34
67
59
59
17
9
17
9
17
50
17
17
17
17
% P
% Gln:
0
9
0
17
25
9
9
0
9
9
9
9
9
9
9
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
9
42
0
0
0
9
50
9
59
% S
% Thr:
0
0
0
0
0
42
0
0
0
9
9
42
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _