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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF6
All Species:
23.64
Human Site:
S375
Identified Species:
47.27
UniProt:
Q16630
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16630
NP_008938.2
551
59210
S375
S
G
M
P
T
S
D
S
R
G
P
P
P
T
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117360
588
63452
S412
S
G
M
P
T
S
D
S
R
G
P
P
P
T
D
Dog
Lupus familis
XP_531671
611
65331
S435
S
G
M
P
T
S
D
S
R
G
P
P
P
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6NVF9
551
59134
S375
S
G
M
P
T
S
D
S
R
G
P
P
P
T
D
Rat
Rattus norvegicus
Q5XI29
462
51054
P289
L
N
P
A
F
F
P
P
P
N
A
T
V
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL34
551
59341
S375
S
G
I
P
T
S
D
S
R
G
P
P
P
T
D
Frog
Xenopus laevis
Q6DDW4
548
59387
S371
A
G
M
T
S
S
D
S
R
G
P
P
P
S
D
Zebra Danio
Brachydanio rerio
Q6NWC6
545
58757
S368
P
G
N
N
M
P
S
S
D
G
R
G
P
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSH4
652
71076
P409
N
M
T
P
Q
H
G
P
P
P
Q
F
A
Q
H
Honey Bee
Apis mellifera
XP_624359
752
82027
H545
G
P
P
H
G
Q
P
H
G
P
P
H
V
P
P
Nematode Worm
Caenorhab. elegans
NP_501551
489
53643
G313
M
G
I
Q
P
M
M
G
M
N
A
P
P
P
M
Sea Urchin
Strong. purpuratus
XP_782654
898
96357
Q708
P
Q
Q
A
P
P
Q
Q
D
R
T
M
Y
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.7
87.8
N.A.
99.6
44.8
N.A.
N.A.
96.7
88.3
84.3
N.A.
42.3
41.3
31.7
33.3
Protein Similarity:
100
N.A.
93.7
88.7
N.A.
99.8
57.1
N.A.
N.A.
97.6
93.2
90.1
N.A.
53.2
49.4
45.9
41.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
0
N.A.
N.A.
93.3
73.3
26.6
N.A.
6.6
6.6
20
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
0
N.A.
N.A.
100
93.3
26.6
N.A.
13.3
6.6
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
17
0
0
0
0
0
0
17
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
50
0
17
0
0
0
0
9
50
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
9
9
0
0
0
0
0
9
0
0
0
% F
% Gly:
9
67
0
0
9
0
9
9
9
59
0
9
0
9
0
% G
% His:
0
0
0
9
0
9
0
9
0
0
0
9
0
0
9
% H
% Ile:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
9
9
42
0
9
9
9
0
9
0
0
9
0
0
9
% M
% Asn:
9
9
9
9
0
0
0
0
0
17
0
0
0
0
0
% N
% Pro:
17
9
17
50
17
17
17
17
17
17
59
59
67
25
25
% P
% Gln:
0
9
9
9
9
9
9
9
0
0
9
0
0
9
9
% Q
% Arg:
0
0
0
0
0
0
0
0
50
9
9
0
0
0
0
% R
% Ser:
42
0
0
0
9
50
9
59
0
0
0
0
0
9
0
% S
% Thr:
0
0
9
9
42
0
0
0
0
0
9
9
0
42
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _