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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF6
All Species:
41.21
Human Site:
S443
Identified Species:
82.42
UniProt:
Q16630
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16630
NP_008938.2
551
59210
S443
A
S
A
G
D
Y
G
S
A
I
E
T
L
V
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117360
588
63452
S480
A
S
A
G
D
Y
G
S
A
I
E
T
L
V
T
Dog
Lupus familis
XP_531671
611
65331
S503
A
S
A
G
D
Y
G
S
A
I
E
T
L
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6NVF9
551
59134
S443
A
S
A
G
D
Y
G
S
A
I
E
T
L
V
T
Rat
Rattus norvegicus
Q5XI29
462
51054
D357
A
S
A
G
D
Y
S
D
A
I
E
T
L
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL34
551
59341
S443
A
S
A
G
D
Y
G
S
A
I
E
T
L
V
T
Frog
Xenopus laevis
Q6DDW4
548
59387
S439
A
S
A
G
D
Y
G
S
A
I
E
T
L
V
T
Zebra Danio
Brachydanio rerio
Q6NWC6
545
58757
S436
A
S
A
A
D
Y
G
S
A
I
E
T
L
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSH4
652
71076
S477
A
A
A
G
E
Y
S
S
A
I
E
T
L
V
T
Honey Bee
Apis mellifera
XP_624359
752
82027
S613
A
A
A
G
E
Y
A
S
A
I
E
T
L
V
T
Nematode Worm
Caenorhab. elegans
NP_501551
489
53643
T381
A
E
F
E
D
V
M
T
R
N
Q
T
V
S
S
Sea Urchin
Strong. purpuratus
XP_782654
898
96357
S776
A
S
S
G
A
F
T
S
A
I
D
T
L
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.7
87.8
N.A.
99.6
44.8
N.A.
N.A.
96.7
88.3
84.3
N.A.
42.3
41.3
31.7
33.3
Protein Similarity:
100
N.A.
93.7
88.7
N.A.
99.8
57.1
N.A.
N.A.
97.6
93.2
90.1
N.A.
53.2
49.4
45.9
41.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
80
N.A.
N.A.
100
100
93.3
N.A.
80
80
20
60
P-Site Similarity:
100
N.A.
100
100
N.A.
100
86.6
N.A.
N.A.
100
100
93.3
N.A.
93.3
93.3
46.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
100
17
84
9
9
0
9
0
92
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
75
0
0
9
0
0
9
0
0
0
0
% D
% Glu:
0
9
0
9
17
0
0
0
0
0
84
0
0
9
0
% E
% Phe:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
84
0
0
59
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
92
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
92
9
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
75
9
0
0
0
17
84
0
0
0
0
0
9
9
% S
% Thr:
0
0
0
0
0
0
9
9
0
0
0
100
0
0
92
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
9
75
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
84
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _