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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF6
All Species:
23.33
Human Site:
Y395
Identified Species:
46.67
UniProt:
Q16630
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16630
NP_008938.2
551
59210
Y395
P
P
Y
D
R
G
D
Y
G
P
P
G
R
E
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117360
588
63452
Y432
P
P
Y
D
R
G
D
Y
G
P
P
G
R
E
M
Dog
Lupus familis
XP_531671
611
65331
Y455
P
P
Y
D
R
G
D
Y
G
P
P
G
R
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q6NVF9
551
59134
Y395
P
P
Y
D
R
G
D
Y
G
P
P
G
R
E
M
Rat
Rattus norvegicus
Q5XI29
462
51054
N309
M
K
A
S
T
P
Y
N
H
H
G
S
R
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL34
551
59341
Y395
P
P
Y
D
R
G
D
Y
G
P
P
G
R
E
M
Frog
Xenopus laevis
Q6DDW4
548
59387
Y391
P
P
Y
E
R
G
D
Y
G
P
P
G
R
D
M
Zebra Danio
Brachydanio rerio
Q6NWC6
545
58757
D388
R
P
P
P
Y
D
R
D
F
P
G
G
R
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSH4
652
71076
P429
W
P
P
P
Q
G
K
P
P
G
P
F
P
D
P
Honey Bee
Apis mellifera
XP_624359
752
82027
G565
P
A
A
Q
P
P
Y
G
A
P
G
P
D
H
R
Nematode Worm
Caenorhab. elegans
NP_501551
489
53643
S333
N
R
P
P
Q
L
G
S
M
G
V
Q
P
L
M
Sea Urchin
Strong. purpuratus
XP_782654
898
96357
A728
Y
T
Q
Q
E
Y
R
A
P
S
E
P
D
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.7
87.8
N.A.
99.6
44.8
N.A.
N.A.
96.7
88.3
84.3
N.A.
42.3
41.3
31.7
33.3
Protein Similarity:
100
N.A.
93.7
88.7
N.A.
99.8
57.1
N.A.
N.A.
97.6
93.2
90.1
N.A.
53.2
49.4
45.9
41.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
6.6
N.A.
N.A.
100
86.6
33.3
N.A.
20
13.3
6.6
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
N.A.
100
100
40
N.A.
33.3
13.3
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
17
0
0
0
0
9
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
42
0
9
50
9
0
0
0
0
17
34
0
% D
% Glu:
0
0
0
9
9
0
0
0
0
0
9
0
0
42
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
59
9
9
50
17
25
59
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
9
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% L
% Met:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
67
% M
% Asn:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
59
67
25
25
9
17
0
9
17
67
59
17
17
0
9
% P
% Gln:
0
0
9
17
17
0
0
0
0
0
0
9
0
0
9
% Q
% Arg:
9
9
0
0
50
0
17
0
0
0
0
0
67
9
9
% R
% Ser:
0
0
0
9
0
0
0
9
0
9
0
9
0
0
9
% S
% Thr:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
50
0
9
9
17
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _