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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMN1
All Species:
40
Human Site:
Y268
Identified Species:
80
UniProt:
Q16637
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16637
NP_000335.1
294
31849
Y268
G
S
M
L
I
S
W
Y
M
S
G
Y
H
T
G
Chimpanzee
Pan troglodytes
XP_001156488
297
32138
Y271
G
S
M
L
I
S
W
Y
M
S
G
Y
H
T
G
Rhesus Macaque
Macaca mulatta
XP_001103970
294
32278
Y268
G
S
M
L
I
L
W
Y
M
R
G
Y
H
T
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97801
288
31236
Y263
G
S
M
L
I
S
W
Y
M
S
G
Y
H
T
G
Rat
Rattus norvegicus
O35876
289
31175
Y263
G
S
M
L
I
S
W
Y
M
S
G
Y
H
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512480
286
31243
Y261
G
S
M
L
I
A
W
Y
M
S
G
Y
H
T
G
Chicken
Gallus gallus
NP_989530
264
29188
G239
L
I
A
W
Y
M
S
G
Y
H
T
G
Y
Y
L
Frog
Xenopus laevis
NP_001082386
282
31341
Y254
G
S
M
L
I
S
W
Y
M
S
G
Y
H
T
G
Zebra Danio
Brachydanio rerio
Q9W6S8
281
30968
Y253
G
S
M
L
I
S
W
Y
M
S
G
Y
H
T
G
Tiger Blowfish
Takifugu rubipres
NP_001129352
278
30764
Y250
G
S
M
L
I
S
W
Y
M
S
G
Y
H
T
G
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001021034
207
22893
M182
Q
K
E
A
M
N
S
M
L
M
S
W
Y
M
S
Sea Urchin
Strong. purpuratus
XP_781229
375
41606
Y292
H
S
M
L
M
S
W
Y
M
S
G
Y
H
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
92.5
N.A.
N.A.
81.6
79.9
N.A.
63.2
53.7
52
51.7
47.9
N.A.
N.A.
26.1
36
Protein Similarity:
100
98.9
94.5
N.A.
N.A.
86
86.7
N.A.
73.8
67
63.9
60.8
60.8
N.A.
N.A.
36.7
48
P-Site Identity:
100
100
86.6
N.A.
N.A.
100
100
N.A.
93.3
0
100
100
100
N.A.
N.A.
0
86.6
P-Site Similarity:
100
100
86.6
N.A.
N.A.
100
100
N.A.
100
6.6
100
100
100
N.A.
N.A.
33.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
75
0
0
0
0
0
0
9
0
0
84
9
0
0
84
% G
% His:
9
0
0
0
0
0
0
0
0
9
0
0
84
0
0
% H
% Ile:
0
9
0
0
75
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
84
0
9
0
0
9
0
0
0
0
0
9
% L
% Met:
0
0
84
0
17
9
0
9
84
9
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
84
0
0
0
67
17
0
0
75
9
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
0
0
84
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
9
0
0
84
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
84
9
0
0
84
17
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _