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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTGIS
All Species:
16.36
Human Site:
S20
Identified Species:
40
UniProt:
Q16647
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16647
NP_000952.1
500
57104
S20
L
L
L
L
L
L
L
S
R
R
R
T
R
R
P
Chimpanzee
Pan troglodytes
XP_514713
657
74033
Q177
G
V
V
I
H
M
L
Q
E
K
R
S
R
R
P
Rhesus Macaque
Macaca mulatta
XP_001098575
500
56976
S20
L
L
L
L
L
L
L
S
R
R
R
T
R
R
P
Dog
Lupus familis
XP_543043
543
61103
G63
M
L
G
I
K
A
P
G
E
D
Q
K
R
R
P
Cat
Felis silvestris
Mouse
Mus musculus
O35074
501
57028
S21
L
L
L
L
L
L
L
S
R
R
R
A
R
R
P
Rat
Rattus norvegicus
Q62969
501
57109
S21
L
L
L
L
L
L
L
S
R
R
R
A
R
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507523
486
55712
P8
L
L
L
R
S
S
H
P
G
E
P
P
L
D
R
Chicken
Gallus gallus
NP_001005571
510
58909
G23
L
G
G
L
Y
V
L
G
T
F
R
R
R
R
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001104630
480
55221
Y19
S
I
L
V
I
V
L
Y
G
R
R
T
R
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMT5
502
57253
I14
A
L
F
V
I
A
A
I
L
A
L
I
Y
V
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.8
97.4
78.4
N.A.
85.8
83.8
N.A.
63.5
46.4
N.A.
47.4
N.A.
20.7
N.A.
N.A.
N.A.
Protein Similarity:
100
75.1
98.4
85.6
N.A.
92.4
91
N.A.
77
63.3
N.A.
67
N.A.
40.6
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
100
26.6
N.A.
93.3
93.3
N.A.
20
46.6
N.A.
46.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
100
46.6
N.A.
93.3
93.3
N.A.
20
53.3
N.A.
73.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
20
10
0
0
10
0
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
20
10
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
10
% F
% Gly:
10
10
20
0
0
0
0
20
20
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
20
20
0
0
10
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
10
0
10
0
0
0
% K
% Leu:
60
70
60
50
40
40
70
0
10
0
10
0
10
0
0
% L
% Met:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
10
0
0
10
10
0
0
70
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
40
50
70
10
80
80
20
% R
% Ser:
10
0
0
0
10
10
0
40
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
30
0
0
0
% T
% Val:
0
10
10
20
0
20
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
10
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _