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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK6
All Species:
18.48
Human Site:
S451
Identified Species:
40.67
UniProt:
Q16659
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16659
NP_002739.1
721
82681
S451
C
N
Y
K
T
R
S
S
S
Y
L
D
N
L
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083937
721
82621
S451
C
N
Y
K
M
R
S
S
S
Y
L
D
N
L
V
Dog
Lupus familis
XP_535486
722
82803
S451
C
N
Y
K
T
R
S
S
S
Y
L
D
N
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61532
720
82181
S451
C
N
Y
K
T
R
S
S
P
Y
L
D
N
L
V
Rat
Rattus norvegicus
P27704
720
82256
P451
C
N
Y
K
T
R
S
P
S
Y
L
D
N
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517230
448
51758
S204
P
K
L
I
I
D
L
S
N
W
K
E
Q
S
K
Chicken
Gallus gallus
Q5F3W3
721
82729
S451
C
N
Y
K
M
R
S
S
S
Y
L
D
N
L
V
Frog
Xenopus laevis
P26696
361
41238
K117
L
M
E
T
D
L
Y
K
L
L
K
T
Q
H
L
Zebra Danio
Brachydanio rerio
NP_001039017
729
83177
P449
C
N
Y
K
A
V
S
P
S
Y
L
D
N
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792156
763
86571
P478
K
E
M
M
S
M
D
P
N
N
L
E
D
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00772
484
55617
V239
I
F
K
G
K
D
Y
V
N
Q
L
N
Q
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
98.4
N.A.
94.7
93.9
N.A.
56.3
92.9
24.8
75.7
N.A.
N.A.
N.A.
N.A.
32.5
Protein Similarity:
100
N.A.
99.7
99.3
N.A.
96.9
96.8
N.A.
58.6
96.5
34.8
85
N.A.
N.A.
N.A.
N.A.
49.9
P-Site Identity:
100
N.A.
93.3
100
N.A.
93.3
93.3
N.A.
6.6
93.3
0
73.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
93.3
100
N.A.
93.3
93.3
N.A.
26.6
93.3
6.6
80
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
64
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
19
10
0
0
0
0
64
10
0
0
% D
% Glu:
0
10
10
0
0
0
0
0
0
0
0
19
0
0
10
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
10
10
0
0
0
0
0
0
0
0
10
10
% I
% Lys:
10
10
10
64
10
0
0
10
0
0
19
0
0
0
10
% K
% Leu:
10
0
10
0
0
10
10
0
10
10
82
0
0
64
19
% L
% Met:
0
10
10
10
19
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
64
0
0
0
0
0
0
28
10
0
10
64
0
0
% N
% Pro:
10
0
0
0
0
0
0
28
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
28
0
0
% Q
% Arg:
0
0
0
0
0
55
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
10
0
64
55
55
0
0
0
0
10
0
% S
% Thr:
0
0
0
10
37
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
55
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
64
0
0
0
19
0
0
64
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _