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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK6
All Species:
19.39
Human Site:
T644
Identified Species:
42.67
UniProt:
Q16659
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16659
NP_002739.1
721
82681
T644
E
D
T
E
M
L
E
T
E
P
V
E
D
G
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083937
721
82621
T644
E
D
T
E
M
L
E
T
E
P
V
E
D
G
K
Dog
Lupus familis
XP_535486
722
82803
T645
E
D
T
E
M
L
E
T
E
P
V
E
D
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61532
720
82181
T643
E
D
S
E
M
L
E
T
E
P
V
E
E
G
K
Rat
Rattus norvegicus
P27704
720
82256
T643
E
D
S
E
M
L
E
T
E
P
V
E
E
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517230
448
51758
K378
M
E
P
A
D
D
G
K
L
G
E
K
E
S
E
Chicken
Gallus gallus
Q5F3W3
721
82729
P644
E
D
A
E
M
L
E
P
E
P
V
E
E
G
K
Frog
Xenopus laevis
P26696
361
41238
D291
N
A
D
P
K
A
L
D
L
L
D
K
M
L
T
Zebra Danio
Brachydanio rerio
NP_001039017
729
83177
L656
D
D
V
E
P
E
I
L
E
P
V
E
V
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792156
763
86571
D659
K
N
T
D
V
V
L
D
K
Q
L
Y
V
H
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00772
484
55617
T413
N
Y
P
K
Q
M
A
T
S
N
S
V
A
P
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
98.4
N.A.
94.7
93.9
N.A.
56.3
92.9
24.8
75.7
N.A.
N.A.
N.A.
N.A.
32.5
Protein Similarity:
100
N.A.
99.7
99.3
N.A.
96.9
96.8
N.A.
58.6
96.5
34.8
85
N.A.
N.A.
N.A.
N.A.
49.9
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
0
80
0
40
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
26.6
86.6
6.6
46.6
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
10
10
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
64
10
10
10
10
0
19
0
0
10
0
28
0
0
% D
% Glu:
55
10
0
64
0
10
55
0
64
0
10
64
37
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
10
0
0
0
55
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
10
10
0
0
10
10
0
0
19
0
0
64
% K
% Leu:
0
0
0
0
0
55
19
10
19
10
10
0
0
10
0
% L
% Met:
10
0
0
0
55
10
0
0
0
0
0
0
10
0
0
% M
% Asn:
19
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
19
10
10
0
0
10
0
64
0
0
0
10
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
19
0
0
0
0
0
10
0
10
0
0
10
10
% S
% Thr:
0
0
37
0
0
0
0
55
0
0
0
0
0
0
10
% T
% Val:
0
0
10
0
10
10
0
0
0
0
64
10
19
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _