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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST3H3
All Species:
49.09
Human Site:
S87
Identified Species:
90
UniProt:
Q16695
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16695
NP_003484.1
136
15508
S87
K
T
D
L
R
F
Q
S
S
A
V
M
A
L
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082339
136
15430
S87
K
T
D
L
R
F
Q
S
S
A
V
M
A
L
Q
Dog
Lupus familis
XP_537880
259
28976
S87
K
T
D
L
R
F
Q
S
S
A
V
M
A
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
NP_038576
136
15370
S87
K
T
D
L
R
F
Q
S
S
A
V
M
A
L
Q
Rat
Rattus norvegicus
P84245
136
15309
S87
K
T
D
L
R
F
Q
S
A
A
I
G
A
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505987
136
15355
S87
K
T
D
L
R
F
Q
S
S
A
V
M
A
L
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
P02302
136
15469
R87
K
T
D
L
R
F
Q
R
S
A
V
M
A
L
Q
Zebra Danio
Brachydanio rerio
NP_001104686
136
15386
S87
K
T
D
L
R
F
Q
S
S
A
V
M
A
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02299
136
15370
S87
K
T
D
L
R
F
Q
S
S
A
V
M
A
L
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P08898
136
15357
S87
K
T
D
L
R
F
Q
S
S
A
V
M
A
L
Q
Sea Urchin
Strong. purpuratus
P06352
136
15483
S87
K
T
E
L
R
F
Q
S
S
A
V
M
A
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P59226
136
15249
S87
K
T
D
L
R
F
Q
S
S
A
V
A
A
L
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P07041
136
15373
S87
K
S
D
L
R
F
Q
S
S
A
I
G
A
L
Q
Conservation
Percent
Protein Identity:
100
N.A.
98.5
50.9
N.A.
96.3
93.3
N.A.
95.5
N.A.
92.6
95.5
N.A.
96.3
N.A.
94.8
94.8
Protein Similarity:
100
N.A.
99.2
51.7
N.A.
97.7
97
N.A.
97
N.A.
94.8
97.7
N.A.
97.7
N.A.
97.7
97
P-Site Identity:
100
N.A.
100
100
N.A.
100
80
N.A.
100
N.A.
93.3
100
N.A.
100
N.A.
100
93.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
93.3
N.A.
100
N.A.
93.3
100
N.A.
100
N.A.
100
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
94.1
N.A.
88.2
Protein Similarity:
N.A.
N.A.
N.A.
97
N.A.
94.1
P-Site Identity:
N.A.
N.A.
N.A.
93.3
N.A.
80
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
N.A.
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
100
0
8
100
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
93
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% I
% Lys:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
100
0
0
0
0
0
0
0
0
0
100
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
77
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
100
% Q
% Arg:
0
0
0
0
100
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
93
93
0
0
0
0
0
0
% S
% Thr:
0
93
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
85
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _