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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP2A13 All Species: 19.7
Human Site: Y487 Identified Species: 61.9
UniProt: Q16696 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16696 NP_000757.2 494 56688 Y487 F A T I P R N Y T M S F L P R
Chimpanzee Pan troglodytes XP_001139878 477 54577 F470 S L R C S L V F L Q L G S S C
Rhesus Macaque Macaca mulatta NP_001035306 494 56490 Y487 F A T I P P N Y T M S F L P R
Dog Lupus familis XP_541606 494 56439 Y487 F G N I P P T Y E L C L K A R
Cat Felis silvestris
Mouse Mus musculus P20852 494 56722 Y487 F A T I P P T Y T M S F L S R
Rat Rattus norvegicus P20812 494 56492 Y487 F A T I P P N Y T M S F L S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P20678 491 56467 Y484 A A N I P R P Y E V S F I P R
Frog Xenopus laevis NP_001085245 496 56377 Y489 F G N V P C P Y K L C F I P R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.2 93.9 60.3 N.A. 88.2 88.8 N.A. N.A. 52.8 54.4 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 80.5 97.5 78.3 N.A. 94.1 94.5 N.A. N.A. 71 72.3 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 93.3 33.3 N.A. 80 86.6 N.A. N.A. 60 40 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 93.3 40 N.A. 80 86.6 N.A. N.A. 73.3 60 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 63 0 0 0 0 0 0 0 0 0 0 0 13 0 % A
% Cys: 0 0 0 13 0 13 0 0 0 0 25 0 0 0 13 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % E
% Phe: 75 0 0 0 0 0 0 13 0 0 0 75 0 0 0 % F
% Gly: 0 25 0 0 0 0 0 0 0 0 0 13 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 75 0 0 0 0 0 0 0 0 25 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 13 0 0 0 13 0 0 % K
% Leu: 0 13 0 0 0 13 0 0 13 25 13 13 50 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % M
% Asn: 0 0 38 0 0 0 38 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 88 50 25 0 0 0 0 0 0 50 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % Q
% Arg: 0 0 13 0 0 25 0 0 0 0 0 0 0 0 88 % R
% Ser: 13 0 0 0 13 0 0 0 0 0 63 0 13 38 0 % S
% Thr: 0 0 50 0 0 0 25 0 50 0 0 0 0 0 0 % T
% Val: 0 0 0 13 0 0 13 0 0 13 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 88 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _