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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKD
All Species:
18.79
Human Site:
T493
Identified Species:
41.33
UniProt:
Q16760
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16760
NP_003639.2
1214
134525
T493
A
H
L
S
K
I
L
T
S
D
Q
H
S
V
V
Chimpanzee
Pan troglodytes
XP_001151474
1220
134870
E504
T
K
I
L
N
S
D
E
H
A
V
V
I
S
S
Rhesus Macaque
Macaca mulatta
XP_001114920
1167
129871
T449
A
H
L
S
K
I
L
T
S
D
Q
H
S
V
V
Dog
Lupus familis
XP_543293
1324
146248
T603
A
H
L
S
K
I
L
T
S
D
Q
H
S
V
V
Cat
Felis silvestris
Mouse
Mus musculus
NP_808314
1220
135190
T493
A
H
L
S
K
I
L
T
S
D
Q
H
S
V
V
Rat
Rattus norvegicus
XP_347259
1196
133109
T473
A
H
L
S
K
I
L
T
S
D
Q
H
S
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507672
1254
138458
D534
L
A
K
I
L
N
S
D
Q
H
S
V
V
I
S
Chicken
Gallus gallus
XP_001232791
1333
149344
D611
L
A
K
I
L
N
S
D
Q
H
S
V
V
I
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693512
1148
127826
G438
V
F
D
L
M
N
G
G
P
Q
L
G
L
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8JQ65
1895
211641
T525
F
I
V
E
T
N
D
T
Q
T
L
I
R
S
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202627
1158
127377
L431
L
N
L
L
L
Q
T
L
K
V
E
A
Q
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.2
93.4
85.1
N.A.
93.7
90.2
N.A.
66.9
63.9
N.A.
60.9
N.A.
34.8
N.A.
N.A.
53.3
Protein Similarity:
100
76.3
94.1
87.8
N.A.
96.4
93.3
N.A.
77.4
73.8
N.A.
71.6
N.A.
46.5
N.A.
N.A.
65.8
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
0
0
N.A.
0
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
6.6
6.6
N.A.
6.6
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
19
0
0
0
0
0
0
0
10
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
19
19
0
46
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
10
0
0
10
0
0
0
0
% E
% Phe:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
10
0
0
0
10
0
0
0
% G
% His:
0
46
0
0
0
0
0
0
10
19
0
46
0
0
0
% H
% Ile:
0
10
10
19
0
46
0
0
0
0
0
10
10
19
0
% I
% Lys:
0
10
19
0
46
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
28
0
55
28
28
0
46
10
0
0
19
0
10
0
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
37
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
28
10
46
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% R
% Ser:
0
0
0
46
0
10
19
0
46
0
19
0
46
19
28
% S
% Thr:
10
0
0
0
10
0
10
55
0
10
0
0
0
0
19
% T
% Val:
10
0
10
0
0
0
0
0
0
10
10
28
19
46
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _