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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TST
All Species:
36.97
Human Site:
S174
Identified Species:
67.78
UniProt:
Q16762
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16762
NP_003303.2
297
33429
S174
Q
V
L
E
N
L
E
S
K
R
F
Q
L
V
D
Chimpanzee
Pan troglodytes
XP_001159714
297
33424
S174
Q
V
L
E
N
L
E
S
K
R
F
Q
L
V
D
Rhesus Macaque
Macaca mulatta
XP_001086543
308
34591
S174
Q
V
L
E
N
L
E
S
K
R
F
Q
L
V
D
Dog
Lupus familis
XP_538396
297
33693
S174
Q
V
L
E
N
L
E
S
K
R
F
Q
L
V
D
Cat
Felis silvestris
Mouse
Mus musculus
P52196
297
33447
S174
Q
V
L
E
N
L
Q
S
K
R
F
Q
L
V
D
Rat
Rattus norvegicus
P24329
297
33388
S174
Q
V
L
E
N
L
Q
S
K
R
F
Q
L
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517033
297
32917
S175
D
I
K
E
N
V
E
S
R
R
F
Q
V
V
D
Chicken
Gallus gallus
P25324
289
32268
N170
T
F
E
Q
A
M
E
N
V
G
S
K
K
F
Q
Frog
Xenopus laevis
NP_001088417
294
33239
S174
D
I
L
R
N
I
D
S
K
E
F
Q
L
V
D
Zebra Danio
Brachydanio rerio
NP_001082815
296
32900
T173
D
V
L
N
N
I
K
T
K
E
F
Q
V
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91247
277
30681
E158
V
Q
S
D
S
K
A
E
G
I
R
C
K
D
A
Sea Urchin
Strong. purpuratus
XP_784555
302
33055
T173
D
M
T
G
N
L
N
T
N
K
F
Q
V
M
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08686
304
34200
A178
L
V
K
S
G
E
L
A
K
K
F
N
A
F
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
94.4
91.5
N.A.
90.9
90.9
N.A.
60.9
70
60.6
56.2
N.A.
N.A.
N.A.
22.8
46.6
Protein Similarity:
100
100
95.4
95.9
N.A.
95.6
96.3
N.A.
75.7
83.1
76.4
73.4
N.A.
N.A.
N.A.
39.3
62.2
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
60
6.6
60
53.3
N.A.
N.A.
N.A.
0
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
33.3
80
80
N.A.
N.A.
N.A.
13.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
8
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
31
0
0
8
0
0
8
0
0
0
0
0
0
8
85
% D
% Glu:
0
0
8
54
0
8
47
8
0
16
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
85
0
0
16
0
% F
% Gly:
0
0
0
8
8
0
0
0
8
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
16
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
16
0
0
8
8
0
70
16
0
8
16
0
0
% K
% Leu:
8
0
62
0
0
54
8
0
0
0
0
0
54
0
0
% L
% Met:
0
8
0
0
0
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
77
0
8
8
8
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
47
8
0
8
0
0
16
0
0
0
0
77
0
0
8
% Q
% Arg:
0
0
0
8
0
0
0
0
8
54
8
0
0
0
0
% R
% Ser:
0
0
8
8
8
0
0
62
0
0
8
0
0
0
0
% S
% Thr:
8
0
8
0
0
0
0
16
0
0
0
0
0
0
0
% T
% Val:
8
62
0
0
0
8
0
0
8
0
0
0
24
70
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _