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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TST
All Species:
24.55
Human Site:
S241
Identified Species:
45
UniProt:
Q16762
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16762
NP_003303.2
297
33429
S241
Q
T
K
K
V
D
L
S
Q
P
L
I
A
T
C
Chimpanzee
Pan troglodytes
XP_001159714
297
33424
S241
Q
T
K
K
V
D
L
S
Q
P
L
I
A
T
C
Rhesus Macaque
Macaca mulatta
XP_001086543
308
34591
S252
Q
T
K
K
V
D
L
S
Q
P
L
I
A
T
C
Dog
Lupus familis
XP_538396
297
33693
A241
E
A
K
K
V
N
L
A
Q
P
L
I
A
T
C
Cat
Felis silvestris
Mouse
Mus musculus
P52196
297
33447
S241
Q
D
K
K
V
D
L
S
Q
P
L
I
A
T
C
Rat
Rattus norvegicus
P24329
297
33388
S241
Q
D
K
K
V
D
L
S
Q
P
L
I
A
T
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517033
297
32917
S241
R
E
K
K
V
D
L
S
Q
P
L
V
A
T
C
Chicken
Gallus gallus
P25324
289
32268
V234
Q
M
F
R
E
K
K
V
D
L
S
K
P
L
T
Frog
Xenopus laevis
NP_001088417
294
33239
L239
F
Q
L
K
G
I
D
L
D
K
P
L
T
I
T
Zebra Danio
Brachydanio rerio
NP_001082815
296
32900
Q240
Q
Q
A
G
V
D
L
Q
K
P
F
W
V
T
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91247
277
30681
I222
L
A
A
A
R
S
G
I
V
A
K
L
Y
N
G
Sea Urchin
Strong. purpuratus
XP_784555
302
33055
S244
A
D
S
G
I
D
L
S
G
P
V
T
A
T
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08686
304
34200
F245
L
E
K
A
L
K
D
F
H
C
T
L
D
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
94.4
91.5
N.A.
90.9
90.9
N.A.
60.9
70
60.6
56.2
N.A.
N.A.
N.A.
22.8
46.6
Protein Similarity:
100
100
95.4
95.9
N.A.
95.6
96.3
N.A.
75.7
83.1
76.4
73.4
N.A.
N.A.
N.A.
39.3
62.2
P-Site Identity:
100
100
100
73.3
N.A.
93.3
93.3
N.A.
80
6.6
6.6
46.6
N.A.
N.A.
N.A.
0
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
13.3
13.3
53.3
N.A.
N.A.
N.A.
6.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
16
16
0
0
0
8
0
8
0
0
62
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
70
% C
% Asp:
0
24
0
0
0
62
16
0
16
0
0
0
8
0
0
% D
% Glu:
8
16
0
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
8
0
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
16
8
0
8
0
8
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
8
0
0
0
47
0
8
0
% I
% Lys:
0
0
62
62
0
16
8
0
8
8
8
8
0
0
0
% K
% Leu:
16
0
8
0
8
0
70
8
0
8
54
24
0
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
70
8
0
8
8
0
% P
% Gln:
54
16
0
0
0
0
0
8
54
0
0
0
0
0
0
% Q
% Arg:
8
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
8
0
54
0
0
8
0
0
0
8
% S
% Thr:
0
24
0
0
0
0
0
0
0
0
8
8
8
70
16
% T
% Val:
0
0
0
0
62
0
0
8
8
0
8
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _