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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TST
All Species:
30.3
Human Site:
T218
Identified Species:
55.56
UniProt:
Q16762
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16762
NP_003303.2
297
33429
T218
M
P
F
M
D
F
L
T
E
D
G
F
E
K
G
Chimpanzee
Pan troglodytes
XP_001159714
297
33424
T218
M
P
F
M
D
F
L
T
E
D
G
F
E
K
G
Rhesus Macaque
Macaca mulatta
XP_001086543
308
34591
T229
M
P
F
M
D
F
L
T
E
D
G
F
E
K
S
Dog
Lupus familis
XP_538396
297
33693
T218
M
P
F
M
D
F
L
T
E
D
G
F
E
K
S
Cat
Felis silvestris
Mouse
Mus musculus
P52196
297
33447
T218
M
P
F
M
D
F
L
T
K
D
G
F
E
K
S
Rat
Rattus norvegicus
P24329
297
33388
T218
V
P
F
M
N
F
L
T
E
D
G
F
E
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517033
297
32917
T218
M
P
F
T
D
F
L
T
E
Q
G
L
E
K
S
Chicken
Gallus gallus
P25324
289
32268
L213
N
M
P
F
S
T
F
L
T
E
S
G
H
E
K
Frog
Xenopus laevis
NP_001088417
294
33239
T217
L
P
F
T
S
F
L
T
E
E
G
Y
E
K
S
Zebra Danio
Brachydanio rerio
NP_001082815
296
32900
D216
M
P
F
P
S
F
M
D
P
E
S
G
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91247
277
30681
V201
I
K
V
G
D
T
V
V
I
S
C
G
I
G
L
Sea Urchin
Strong. purpuratus
XP_784555
302
33055
N216
V
P
F
S
T
L
L
N
D
D
D
S
E
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08686
304
34200
T224
G
S
L
L
D
P
E
T
K
T
Y
P
E
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
94.4
91.5
N.A.
90.9
90.9
N.A.
60.9
70
60.6
56.2
N.A.
N.A.
N.A.
22.8
46.6
Protein Similarity:
100
100
95.4
95.9
N.A.
95.6
96.3
N.A.
75.7
83.1
76.4
73.4
N.A.
N.A.
N.A.
39.3
62.2
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
80
N.A.
73.3
0
60
26.6
N.A.
N.A.
N.A.
6.6
33.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
73.3
13.3
80
46.6
N.A.
N.A.
N.A.
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
62
0
0
8
8
54
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
54
24
0
0
77
16
0
% E
% Phe:
0
0
77
8
0
70
8
0
0
0
0
47
0
0
0
% F
% Gly:
8
0
0
8
0
0
0
0
0
0
62
24
0
8
24
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
16
0
0
0
0
62
8
% K
% Leu:
8
0
8
8
0
8
70
8
0
0
0
8
8
0
8
% L
% Met:
54
8
0
47
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
77
8
8
0
8
0
0
8
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% R
% Ser:
0
8
0
8
24
0
0
0
0
8
16
8
0
0
47
% S
% Thr:
0
0
0
16
8
16
0
70
8
8
0
0
0
0
0
% T
% Val:
16
0
8
0
0
0
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _