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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2S All Species: 16.06
Human Site: T180 Identified Species: 22.08
UniProt: Q16763 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16763 NP_055316.2 222 23845 T180 S G T E A S S T D P G A P G G
Chimpanzee Pan troglodytes XP_512912 260 27794 T218 S G T A A S S T D P G A P G G
Rhesus Macaque Macaca mulatta XP_001087564 222 23769 T180 S G T A A S S T D P G A P G G
Dog Lupus familis XP_541410 223 23893 S180 A S G G A T P S T D P M A P G
Cat Felis silvestris
Mouse Mus musculus Q921J4 223 24164 S180 A S G A S A S S A D P M I P G
Rat Rattus norvegicus B5DFI8 223 24196 S180 A S G A S A S S T D P M T P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514616 160 17170 K136 A D G P M A K K H A G E R D K
Chicken Gallus gallus
Frog Xenopus laevis Q8AVU2 211 23340 G180 A S T P V V S G D G P M A K K
Zebra Danio Brachydanio rerio Q4V908 221 24130 P180 P K K H A G D P N K R V V G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VX25 209 23319 H183 G G P S T K K H A G L D K K L
Honey Bee Apis mellifera XP_392244 212 23084 P185 S E V G G P L P K K H A G D K
Nematode Worm Caenorhab. elegans P35129 147 16687 R125 P L V P E I A R I Y K T D R E
Sea Urchin Strong. purpuratus XP_783214 217 24076 S185 P S T S G S N S Q H G P A A K
Poplar Tree Populus trichocarpa XP_002308845 268 29066 N179 A L N V D Q S N T S V L N N G
Maize Zea mays NP_001132661 252 27334 S179 T A L N V D K S S T A S S K N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FF66 251 27381 N179 A L N V G Q T N N E T P G A A
Baker's Yeast Sacchar. cerevisiae P52490 153 17450 K131 D V A E D W I K N E Q G A K A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85 99.5 95 N.A. 92.8 93.7 N.A. 63.5 N.A. 78.3 65.3 N.A. 57.2 60.8 28.8 60.3
Protein Similarity: 100 85 99.5 95.5 N.A. 93.2 93.7 N.A. 66.6 N.A. 86.4 76.1 N.A. 70.7 73.8 41.4 75.2
P-Site Identity: 100 93.3 93.3 13.3 N.A. 13.3 13.3 N.A. 6.6 N.A. 20 13.3 N.A. 6.6 13.3 0 20
P-Site Similarity: 100 93.3 93.3 33.3 N.A. 40 40 N.A. 20 N.A. 26.6 20 N.A. 6.6 13.3 6.6 33.3
Percent
Protein Identity: 46.2 48 N.A. 49.4 33.7 N.A.
Protein Similarity: 60.4 62.3 N.A. 62.9 45.9 N.A.
P-Site Identity: 13.3 0 N.A. 0 6.6 N.A.
P-Site Similarity: 20 20 N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 42 6 6 24 30 18 6 0 12 6 6 24 24 12 18 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 6 0 0 12 6 6 0 24 18 0 6 6 12 0 % D
% Glu: 0 6 0 12 6 0 0 0 0 12 0 6 0 0 6 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 6 24 24 12 18 6 0 6 0 12 30 6 12 24 42 % G
% His: 0 0 0 6 0 0 0 6 6 6 6 0 0 0 0 % H
% Ile: 0 0 0 0 0 6 6 0 6 0 0 0 6 0 0 % I
% Lys: 0 6 6 0 0 6 18 12 6 12 6 0 6 24 24 % K
% Leu: 0 18 6 0 0 0 6 0 0 0 6 6 0 0 6 % L
% Met: 0 0 0 0 6 0 0 0 0 0 0 24 0 0 0 % M
% Asn: 0 0 12 6 0 0 6 12 18 0 0 0 6 6 6 % N
% Pro: 18 0 6 18 0 6 6 12 0 18 24 12 18 18 0 % P
% Gln: 0 0 0 0 0 12 0 0 6 0 6 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 6 0 0 6 0 6 6 0 % R
% Ser: 24 30 0 12 12 24 42 30 6 6 0 6 6 0 0 % S
% Thr: 6 0 30 0 6 6 6 18 18 6 6 6 6 0 0 % T
% Val: 0 6 12 12 12 6 0 0 0 0 6 6 6 0 0 % V
% Trp: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _