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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAGH
All Species:
33.94
Human Site:
S168
Identified Species:
62.22
UniProt:
Q16775
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16775
NP_001035517.1
308
33806
S168
G
H
I
C
Y
F
V
S
K
P
G
G
S
E
P
Chimpanzee
Pan troglodytes
XP_510739
282
31321
S142
G
H
I
C
Y
F
V
S
K
P
R
G
S
E
P
Rhesus Macaque
Macaca mulatta
XP_001090907
308
33886
S168
G
H
V
C
Y
F
V
S
R
P
G
G
S
E
P
Dog
Lupus familis
XP_537013
309
33857
S169
G
H
I
C
Y
F
V
S
K
P
N
S
S
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99KB8
309
34066
S169
G
H
I
C
Y
F
V
S
K
P
G
S
S
E
P
Rat
Rattus norvegicus
O35952
309
34091
S169
G
H
I
C
Y
F
V
S
K
P
G
S
S
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI23
310
34206
T170
G
H
I
C
Y
Y
V
T
K
P
N
S
S
E
P
Frog
Xenopus laevis
NP_001089873
260
29031
K143
L
F
V
A
G
C
G
K
F
F
E
G
T
A
E
Zebra Danio
Brachydanio rerio
Q6P963
303
33787
T163
G
H
I
C
Y
F
V
T
K
E
N
S
T
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730568
348
38839
T210
G
H
I
C
Y
H
I
T
A
Q
Q
G
S
G
E
Honey Bee
Apis mellifera
XP_623458
288
32956
T153
G
H
I
C
Y
Y
I
T
E
N
Q
D
V
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783848
258
28463
F143
F
L
S
G
C
G
R
F
F
E
G
T
P
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O24496
258
28773
G141
G
D
T
L
F
V
A
G
C
G
K
F
F
E
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
96.4
86.4
N.A.
87.3
84.7
N.A.
N.A.
74.8
68.5
71.4
N.A.
48.5
52.2
N.A.
51.9
Protein Similarity:
100
91.2
98.6
93.5
N.A.
94.8
93.1
N.A.
N.A.
86.7
78.5
84
N.A.
64.3
67.8
N.A.
65.5
P-Site Identity:
100
93.3
86.6
86.6
N.A.
93.3
93.3
N.A.
N.A.
73.3
6.6
60
N.A.
46.6
33.3
N.A.
6.6
P-Site Similarity:
100
93.3
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
20
73.3
N.A.
60
60
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
8
0
0
0
0
8
16
% A
% Cys:
0
0
0
77
8
8
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
16
8
0
0
70
16
% E
% Phe:
8
8
0
0
8
54
0
8
16
8
0
8
8
0
0
% F
% Gly:
85
0
0
8
8
8
8
8
0
8
39
39
0
8
8
% G
% His:
0
77
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
70
0
0
0
16
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
54
0
8
0
0
0
0
% K
% Leu:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
24
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
54
0
0
8
8
54
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
16
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
0
47
0
0
0
39
62
0
0
% S
% Thr:
0
0
8
0
0
0
0
31
0
0
0
8
16
0
0
% T
% Val:
0
0
16
0
0
8
62
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
77
16
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _