Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAGH All Species: 30.91
Human Site: S173 Identified Species: 56.67
UniProt: Q16775 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16775 NP_001035517.1 308 33806 S173 F V S K P G G S E P P A V F T
Chimpanzee Pan troglodytes XP_510739 282 31321 S147 F V S K P R G S E P P A V F T
Rhesus Macaque Macaca mulatta XP_001090907 308 33886 S173 F V S R P G G S E P P A V F T
Dog Lupus familis XP_537013 309 33857 S174 F V S K P N S S E P P A V F T
Cat Felis silvestris
Mouse Mus musculus Q99KB8 309 34066 S174 F V S K P G S S E P S A V F T
Rat Rattus norvegicus O35952 309 34091 S174 F V S K P G S S E P S A V F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZI23 310 34206 S175 Y V T K P N S S E P P A V F T
Frog Xenopus laevis NP_001089873 260 29031 T148 C G K F F E G T A E E M Y A A
Zebra Danio Brachydanio rerio Q6P963 303 33787 T168 F V T K E N S T E A P A V F T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730568 348 38839 S215 H I T A Q Q G S G E G A V F T
Honey Bee Apis mellifera XP_623458 288 32956 V158 Y I T E N Q D V P A V F T G D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783848 258 28463 P148 G R F F E G T P D Q M Y A A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O24496 258 28773 F146 V A G C G K F F E G T A E Q M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.2 96.4 86.4 N.A. 87.3 84.7 N.A. N.A. 74.8 68.5 71.4 N.A. 48.5 52.2 N.A. 51.9
Protein Similarity: 100 91.2 98.6 93.5 N.A. 94.8 93.1 N.A. N.A. 86.7 78.5 84 N.A. 64.3 67.8 N.A. 65.5
P-Site Identity: 100 93.3 93.3 86.6 N.A. 86.6 86.6 N.A. N.A. 73.3 6.6 60 N.A. 40 0 N.A. 6.6
P-Site Similarity: 100 93.3 100 86.6 N.A. 86.6 86.6 N.A. N.A. 86.6 13.3 73.3 N.A. 53.3 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 45.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 59.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 0 0 8 16 0 77 8 16 8 % A
% Cys: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 8 % D
% Glu: 0 0 0 8 16 8 0 0 70 16 8 0 8 0 0 % E
% Phe: 54 0 8 16 8 0 8 8 0 0 0 8 0 70 0 % F
% Gly: 8 8 8 0 8 39 39 0 8 8 8 0 0 8 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 54 0 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 8 % M
% Asn: 0 0 0 0 8 24 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 54 0 0 8 8 54 47 0 0 0 0 % P
% Gln: 0 0 0 0 8 16 0 0 0 8 0 0 0 8 0 % Q
% Arg: 0 8 0 8 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 47 0 0 0 39 62 0 0 16 0 0 0 0 % S
% Thr: 0 0 31 0 0 0 8 16 0 0 8 0 8 0 70 % T
% Val: 8 62 0 0 0 0 0 8 0 0 8 0 70 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _