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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAGH All Species: 40
Human Site: T155 Identified Species: 73.33
UniProt: Q16775 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16775 NP_001035517.1 308 33806 T155 L N V K C L A T P C H T S G H
Chimpanzee Pan troglodytes XP_510739 282 31321 T129 L N V K C L A T P C H T S G H
Rhesus Macaque Macaca mulatta XP_001090907 308 33886 T155 L N V K C L A T P C H T S G H
Dog Lupus familis XP_537013 309 33857 T156 L N V K C L S T P C H T S G H
Cat Felis silvestris
Mouse Mus musculus Q99KB8 309 34066 T156 L S V K C L S T P C H T S G H
Rat Rattus norvegicus O35952 309 34091 T156 L S V K C L S T P C H T S G H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZI23 310 34206 T157 L N V K C L C T P C H T S G H
Frog Xenopus laevis NP_001089873 260 29031 L130 N S T E P P A L F T G D T L F
Zebra Danio Brachydanio rerio Q6P963 303 33787 T150 L N V K C L F T P C H T S G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730568 348 38839 T197 L H V K C L S T P C H T T G H
Honey Bee Apis mellifera XP_623458 288 32956 T140 L Q V Q C L S T P C H T T G H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783848 258 28463 F130 P S E A P V V F T G D T L F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O24496 258 28773 N128 V N G K E G E N P A V F T G D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.2 96.4 86.4 N.A. 87.3 84.7 N.A. N.A. 74.8 68.5 71.4 N.A. 48.5 52.2 N.A. 51.9
Protein Similarity: 100 91.2 98.6 93.5 N.A. 94.8 93.1 N.A. N.A. 86.7 78.5 84 N.A. 64.3 67.8 N.A. 65.5
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. N.A. 93.3 6.6 93.3 N.A. 80 73.3 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 26.6 93.3 N.A. 100 93.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 45.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 59.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 31 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 77 0 8 0 0 77 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 8 % D
% Glu: 0 0 8 8 8 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 8 8 0 0 8 0 8 8 % F
% Gly: 0 0 8 0 0 8 0 0 0 8 8 0 0 85 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 77 0 0 0 77 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 77 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 77 0 0 0 0 77 0 8 0 0 0 0 8 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 54 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 16 8 0 0 85 0 0 0 0 0 0 % P
% Gln: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 31 0 0 0 0 39 0 0 0 0 0 62 0 0 % S
% Thr: 0 0 8 0 0 0 0 77 8 8 0 85 31 0 0 % T
% Val: 8 0 77 0 0 8 8 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _