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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAGH
All Species:
38.18
Human Site:
T215
Identified Species:
70
UniProt:
Q16775
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16775
NP_001035517.1
308
33806
T215
L
G
R
L
P
P
D
T
R
V
Y
C
G
H
E
Chimpanzee
Pan troglodytes
XP_510739
282
31321
T189
L
G
R
L
P
P
D
T
R
V
Y
C
G
H
E
Rhesus Macaque
Macaca mulatta
XP_001090907
308
33886
T215
L
G
R
L
P
P
D
T
R
V
Y
C
G
H
E
Dog
Lupus familis
XP_537013
309
33857
T216
L
G
R
L
P
P
D
T
R
V
Y
C
G
H
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99KB8
309
34066
T216
L
G
R
L
P
P
D
T
K
V
Y
C
G
H
E
Rat
Rattus norvegicus
O35952
309
34091
T216
L
G
R
L
P
P
D
T
K
V
I
C
G
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI23
310
34206
T217
L
G
S
L
D
P
E
T
R
V
Y
C
G
H
E
Frog
Xenopus laevis
NP_001089873
260
29031
E187
L
K
F
A
R
H
V
E
P
N
N
D
A
I
K
Zebra Danio
Brachydanio rerio
Q6P963
303
33787
T210
L
G
R
L
P
P
E
T
R
V
Y
C
G
H
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730568
348
38839
T257
L
S
A
L
P
D
A
T
K
V
F
C
G
H
E
Honey Bee
Apis mellifera
XP_623458
288
32956
T198
L
G
S
L
P
N
E
T
K
V
Y
C
G
H
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783848
258
28463
E186
L
S
F
A
L
S
V
E
P
D
N
V
S
I
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O24496
258
28773
L185
V
K
N
L
E
F
A
L
T
V
E
P
N
N
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
96.4
86.4
N.A.
87.3
84.7
N.A.
N.A.
74.8
68.5
71.4
N.A.
48.5
52.2
N.A.
51.9
Protein Similarity:
100
91.2
98.6
93.5
N.A.
94.8
93.1
N.A.
N.A.
86.7
78.5
84
N.A.
64.3
67.8
N.A.
65.5
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
N.A.
80
6.6
93.3
N.A.
60
73.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
86.6
13.3
100
N.A.
73.3
86.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
16
0
0
16
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
77
0
0
0
% C
% Asp:
0
0
0
0
8
8
47
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
0
0
8
0
24
16
0
0
8
0
0
0
77
% E
% Phe:
0
0
16
0
0
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
70
0
0
0
0
0
0
0
0
0
0
77
0
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
77
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
16
0
% I
% Lys:
0
16
0
0
0
0
0
0
31
0
0
0
0
0
8
% K
% Leu:
93
0
0
85
8
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
8
16
0
8
8
0
% N
% Pro:
0
0
0
0
70
62
0
0
16
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
54
0
8
0
0
0
47
0
0
0
0
0
0
% R
% Ser:
0
16
16
0
0
8
0
0
0
0
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
77
8
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
16
0
0
85
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
62
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _