KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAGH
All Species:
17.88
Human Site:
T43
Identified Species:
32.78
UniProt:
Q16775
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16775
NP_001035517.1
308
33806
T43
T
D
L
R
K
N
L
T
V
D
E
G
T
M
K
Chimpanzee
Pan troglodytes
XP_510739
282
31321
A30
M
R
V
E
V
L
P
A
L
T
D
N
Y
M
Y
Rhesus Macaque
Macaca mulatta
XP_001090907
308
33886
T43
T
D
L
R
K
N
L
T
V
D
E
G
T
M
K
Dog
Lupus familis
XP_537013
309
33857
T44
A
D
S
Q
K
S
V
T
V
E
Q
G
T
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99KB8
309
34066
T44
S
D
F
R
K
N
L
T
V
Q
Q
D
I
M
K
Rat
Rattus norvegicus
O35952
309
34091
T44
T
D
F
R
K
N
L
T
V
Q
Q
D
M
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI23
310
34206
T45
H
E
Q
R
K
S
K
T
V
A
Q
A
N
M
K
Frog
Xenopus laevis
NP_001089873
260
29031
P30
K
E
A
A
I
V
D
P
V
Q
P
Q
K
V
V
Zebra Danio
Brachydanio rerio
Q6P963
303
33787
L38
S
A
I
R
K
S
S
L
V
E
Q
S
D
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730568
348
38839
D84
G
M
H
S
T
L
E
D
V
Q
L
E
G
M
E
Honey Bee
Apis mellifera
XP_623458
288
32956
L39
Y
D
M
K
V
Q
I
L
P
A
L
Q
D
N
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783848
258
28463
P30
K
E
A
A
I
V
D
P
V
D
P
E
K
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O24496
258
28773
P30
G
D
A
A
V
V
D
P
V
D
P
E
K
V
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
96.4
86.4
N.A.
87.3
84.7
N.A.
N.A.
74.8
68.5
71.4
N.A.
48.5
52.2
N.A.
51.9
Protein Similarity:
100
91.2
98.6
93.5
N.A.
94.8
93.1
N.A.
N.A.
86.7
78.5
84
N.A.
64.3
67.8
N.A.
65.5
P-Site Identity:
100
6.6
100
53.3
N.A.
60
66.6
N.A.
N.A.
40
6.6
33.3
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
26.6
100
86.6
N.A.
73.3
73.3
N.A.
N.A.
60
20
66.6
N.A.
20
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
24
24
0
0
0
8
0
16
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
54
0
0
0
0
24
8
0
31
8
16
16
0
0
% D
% Glu:
0
24
0
8
0
0
8
0
0
16
16
24
0
0
8
% E
% Phe:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
0
0
0
0
0
0
0
0
24
8
0
0
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
16
0
8
0
0
0
0
0
8
0
8
% I
% Lys:
16
0
0
8
54
0
8
0
0
0
0
0
24
0
54
% K
% Leu:
0
0
16
0
0
16
31
16
8
0
16
0
0
0
8
% L
% Met:
8
8
8
0
0
0
0
0
0
0
0
0
8
70
0
% M
% Asn:
0
0
0
0
0
31
0
0
0
0
0
8
8
8
0
% N
% Pro:
0
0
0
0
0
0
8
24
8
0
24
0
0
0
0
% P
% Gln:
0
0
8
8
0
8
0
0
0
31
39
16
0
0
0
% Q
% Arg:
0
8
0
47
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
0
8
8
0
24
8
0
0
0
0
8
0
0
0
% S
% Thr:
24
0
0
0
8
0
0
47
0
8
0
0
24
0
0
% T
% Val:
0
0
8
0
24
24
8
0
85
0
0
0
0
24
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _