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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAGH All Species: 26.36
Human Site: T97 Identified Species: 48.33
UniProt: Q16775 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16775 NP_001035517.1 308 33806 T97 K H G V K L T T V L T T H H H
Chimpanzee Pan troglodytes XP_510739 282 31321 L73 G V K L T T V L T T H H H W D
Rhesus Macaque Macaca mulatta XP_001090907 308 33886 T97 K H G V K L T T V L T T H H H
Dog Lupus familis XP_537013 309 33857 T98 K H G V R L T T V L T T H H H
Cat Felis silvestris
Mouse Mus musculus Q99KB8 309 34066 T98 K H H V K L T T V L T T H H H
Rat Rattus norvegicus O35952 309 34091 T98 K H R V K L T T V L T T H H H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZI23 310 34206 S99 K H G V K L T S V L T T H H H
Frog Xenopus laevis NP_001089873 260 29031 V73 L V K M V S G V K V Y G G D S
Zebra Danio Brachydanio rerio Q6P963 303 33787 T92 K H G V K L K T V L T T H H H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730568 348 38839 K138 E Q Q L T L S K V L T T H H H
Honey Bee Apis mellifera XP_623458 288 32956 K82 Q N N V S L T K V L T T H H H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783848 258 28463 L73 L V K L T S G L T V C G G D D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O24496 258 28773 I73 I K Q L V P D I K V Y G G S L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.2 96.4 86.4 N.A. 87.3 84.7 N.A. N.A. 74.8 68.5 71.4 N.A. 48.5 52.2 N.A. 51.9
Protein Similarity: 100 91.2 98.6 93.5 N.A. 94.8 93.1 N.A. N.A. 86.7 78.5 84 N.A. 64.3 67.8 N.A. 65.5
P-Site Identity: 100 6.6 100 93.3 N.A. 93.3 93.3 N.A. N.A. 93.3 0 93.3 N.A. 53.3 66.6 N.A. 0
P-Site Similarity: 100 13.3 100 100 N.A. 93.3 93.3 N.A. N.A. 100 13.3 93.3 N.A. 73.3 80 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 45.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 59.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 16 16 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 39 0 0 0 16 0 0 0 0 24 24 0 0 % G
% His: 0 54 8 0 0 0 0 0 0 0 8 8 77 70 70 % H
% Ile: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 54 8 24 0 47 0 8 16 16 0 0 0 0 0 0 % K
% Leu: 16 0 0 31 0 70 0 16 0 70 0 0 0 0 8 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 8 16 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 8 16 8 8 0 0 0 0 0 8 8 % S
% Thr: 0 0 0 0 24 8 54 47 16 8 70 70 0 0 0 % T
% Val: 0 24 0 62 16 0 8 8 70 24 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _