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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAGH
All Species:
30.91
Human Site:
Y218
Identified Species:
56.67
UniProt:
Q16775
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16775
NP_001035517.1
308
33806
Y218
L
P
P
D
T
R
V
Y
C
G
H
E
Y
T
I
Chimpanzee
Pan troglodytes
XP_510739
282
31321
Y192
L
P
P
D
T
R
V
Y
C
G
H
E
Y
T
I
Rhesus Macaque
Macaca mulatta
XP_001090907
308
33886
Y218
L
P
P
D
T
R
V
Y
C
G
H
E
Y
T
I
Dog
Lupus familis
XP_537013
309
33857
Y219
L
P
P
D
T
R
V
Y
C
G
H
E
Y
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q99KB8
309
34066
Y219
L
P
P
D
T
K
V
Y
C
G
H
E
Y
T
V
Rat
Rattus norvegicus
O35952
309
34091
I219
L
P
P
D
T
K
V
I
C
G
H
E
Y
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI23
310
34206
Y220
L
D
P
E
T
R
V
Y
C
G
H
E
Y
T
I
Frog
Xenopus laevis
NP_001089873
260
29031
N190
A
R
H
V
E
P
N
N
D
A
I
K
Q
K
L
Zebra Danio
Brachydanio rerio
Q6P963
303
33787
Y213
L
P
P
E
T
R
V
Y
C
G
H
E
Y
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730568
348
38839
F260
L
P
D
A
T
K
V
F
C
G
H
E
Y
T
L
Honey Bee
Apis mellifera
XP_623458
288
32956
Y201
L
P
N
E
T
K
V
Y
C
G
H
E
Y
T
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783848
258
28463
N189
A
L
S
V
E
P
D
N
V
S
I
Q
K
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O24496
258
28773
E188
L
E
F
A
L
T
V
E
P
N
N
G
K
I
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
96.4
86.4
N.A.
87.3
84.7
N.A.
N.A.
74.8
68.5
71.4
N.A.
48.5
52.2
N.A.
51.9
Protein Similarity:
100
91.2
98.6
93.5
N.A.
94.8
93.1
N.A.
N.A.
86.7
78.5
84
N.A.
64.3
67.8
N.A.
65.5
P-Site Identity:
100
100
100
100
N.A.
86.6
80
N.A.
N.A.
86.6
0
93.3
N.A.
66.6
73.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
93.3
13.3
100
N.A.
86.6
86.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
16
0
0
0
0
0
8
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
77
0
0
0
0
0
0
% C
% Asp:
0
8
8
47
0
0
8
0
8
0
0
0
0
0
0
% D
% Glu:
0
8
0
24
16
0
0
8
0
0
0
77
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
77
0
8
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
77
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
16
0
0
8
47
% I
% Lys:
0
0
0
0
0
31
0
0
0
0
0
8
16
16
0
% K
% Leu:
85
8
0
0
8
0
0
0
0
0
0
0
0
0
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
16
0
8
8
0
0
0
0
% N
% Pro:
0
70
62
0
0
16
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
8
% Q
% Arg:
0
8
0
0
0
47
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
77
8
0
0
0
0
0
0
0
77
0
% T
% Val:
0
0
0
16
0
0
85
0
8
0
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
77
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _