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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAGH
All Species:
30.3
Human Site:
Y269
Identified Species:
55.56
UniProt:
Q16775
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16775
NP_001035517.1
308
33806
Y269
T
L
A
E
E
F
T
Y
N
P
F
M
R
V
R
Chimpanzee
Pan troglodytes
XP_510739
282
31321
Y243
T
L
A
E
E
F
T
Y
N
P
F
M
R
V
R
Rhesus Macaque
Macaca mulatta
XP_001090907
308
33886
Y269
T
L
A
E
E
F
T
Y
N
P
F
M
R
V
R
Dog
Lupus familis
XP_537013
309
33857
Y270
T
I
A
E
E
F
T
Y
N
P
F
M
R
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99KB8
309
34066
Y270
T
L
A
E
E
F
T
Y
N
P
F
M
R
V
K
Rat
Rattus norvegicus
O35952
309
34091
Y270
T
L
A
E
E
F
T
Y
N
P
F
M
R
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI23
310
34206
Y271
T
I
A
E
E
F
T
Y
N
P
F
M
R
V
R
Frog
Xenopus laevis
NP_001089873
260
29031
K230
P
F
M
R
V
R
E
K
S
V
Q
E
H
A
G
Zebra Danio
Brachydanio rerio
Q6P963
303
33787
F264
T
V
A
E
E
F
T
F
N
P
F
M
R
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730568
348
38839
W311
T
I
G
E
E
K
S
W
N
P
F
M
R
V
H
Honey Bee
Apis mellifera
XP_623458
288
32956
T252
T
I
Q
E
E
K
L
T
N
P
F
M
R
V
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783848
258
28463
G227
Y
N
P
F
M
R
V
G
A
K
S
I
Q
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O24496
258
28773
R227
L
E
T
N
P
F
M
R
V
D
K
P
E
I
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
96.4
86.4
N.A.
87.3
84.7
N.A.
N.A.
74.8
68.5
71.4
N.A.
48.5
52.2
N.A.
51.9
Protein Similarity:
100
91.2
98.6
93.5
N.A.
94.8
93.1
N.A.
N.A.
86.7
78.5
84
N.A.
64.3
67.8
N.A.
65.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
0
86.6
N.A.
60
60
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
6.6
100
N.A.
80
66.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
62
0
0
0
0
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% D
% Glu:
0
8
0
77
77
0
8
0
0
0
0
8
8
0
0
% E
% Phe:
0
8
0
8
0
70
0
8
0
0
77
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
24
% H
% Ile:
0
31
0
0
0
0
0
0
0
0
0
8
0
8
0
% I
% Lys:
0
0
0
0
0
16
0
8
0
8
8
0
0
0
16
% K
% Leu:
8
39
0
0
0
0
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
8
0
8
0
8
0
0
0
0
77
0
0
0
% M
% Asn:
0
8
0
8
0
0
0
0
77
0
0
0
0
0
0
% N
% Pro:
8
0
8
0
8
0
0
0
0
77
0
8
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
8
0
8
0
8
% Q
% Arg:
0
0
0
8
0
16
0
8
0
0
0
0
77
0
47
% R
% Ser:
0
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% S
% Thr:
77
0
8
0
0
0
62
8
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
8
0
8
0
8
8
0
0
0
77
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _