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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST2H2AC
All Species:
49.7
Human Site:
Y40
Identified Species:
99.39
UniProt:
Q16777
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16777
NP_003508.1
129
13988
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Chimpanzee
Pan troglodytes
XP_001137950
130
14103
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Rhesus Macaque
Macaca mulatta
XP_001096671
130
14103
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Dog
Lupus familis
XP_540292
148
15901
Y59
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1M2
129
14027
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Rat
Rattus norvegicus
P02262
130
14059
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513003
129
13922
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Chicken
Gallus gallus
P70082
129
13998
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Frog
Xenopus laevis
P06897
130
13948
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Zebra Danio
Brachydanio rerio
Q7ZUY3
142
14983
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P84051
124
13344
Y39
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P16886
126
13432
Y40
R
F
L
R
K
G
N
Y
A
Q
R
V
G
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
97.6
87.1
N.A.
96.1
97.6
N.A.
98.4
99.2
93.8
84.5
N.A.
86.8
N.A.
N.A.
89.9
Protein Similarity:
100
97.6
99.2
87.1
N.A.
97.6
98.4
N.A.
99.2
99.2
96.9
88
N.A.
92.2
N.A.
N.A.
93
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
N.A.
N.A.
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
100
0
0
0
0
100
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
92
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
100
0
0
0
0
0
0
100
0
100
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
92
100
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
100
0
0
100
0
0
0
0
0
0
100
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _