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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIST2H2AC All Species: 50
Human Site: Y51 Identified Species: 100
UniProt: Q16777 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16777 NP_003508.1 129 13988 Y51 V G A G A P V Y M A A V L E Y
Chimpanzee Pan troglodytes XP_001137950 130 14103 Y51 V G A G A P V Y L A A V L E Y
Rhesus Macaque Macaca mulatta XP_001096671 130 14103 Y51 V G A G A P V Y L A A V L E Y
Dog Lupus familis XP_540292 148 15901 Y70 V G A G A P V Y M A A V L E Y
Cat Felis silvestris
Mouse Mus musculus Q8R1M2 129 14027 Y51 V G A G A P V Y L A A V L E Y
Rat Rattus norvegicus P02262 130 14059 Y51 V G A G A P V Y L A A V L E Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513003 129 13922 Y51 V G A G A P V Y L A A V L E Y
Chicken Gallus gallus P70082 129 13998 Y51 V G A G A P V Y M A A V L E Y
Frog Xenopus laevis P06897 130 13948 Y51 V G A G A P V Y L A A V L E Y
Zebra Danio Brachydanio rerio Q7ZUY3 142 14983 Y51 V G A G A P V Y L A A V L E Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P84051 124 13344 Y50 V G A G A P V Y L A A V M E Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P16886 126 13432 Y51 V G A G A P V Y L A A V L E Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 97.6 87.1 N.A. 96.1 97.6 N.A. 98.4 99.2 93.8 84.5 N.A. 86.8 N.A. N.A. 89.9
Protein Similarity: 100 97.6 99.2 87.1 N.A. 97.6 98.4 N.A. 99.2 99.2 96.9 88 N.A. 92.2 N.A. N.A. 93
P-Site Identity: 100 93.3 93.3 100 N.A. 93.3 93.3 N.A. 93.3 100 93.3 93.3 N.A. 86.6 N.A. N.A. 93.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 100 N.A. N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 100 0 100 0 0 0 0 100 100 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 100 0 100 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 75 0 0 0 92 0 0 % L
% Met: 0 0 0 0 0 0 0 0 25 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 100 0 0 0 0 0 100 0 0 0 0 100 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 100 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _