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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST2H2BE
All Species:
40.61
Human Site:
S56
Identified Species:
81.21
UniProt:
Q16778
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16778
NP_003519.1
126
13920
S56
V
H
P
D
T
G
I
S
S
K
A
M
G
I
M
Chimpanzee
Pan troglodytes
XP_518302
152
16759
S82
V
H
P
D
T
G
I
S
S
K
A
M
G
I
M
Rhesus Macaque
Macaca mulatta
XP_001090500
154
17046
S84
V
H
P
D
T
G
I
S
S
K
A
M
G
I
M
Dog
Lupus familis
XP_545412
137
15110
S56
V
H
P
D
T
G
I
S
S
K
A
M
G
I
M
Cat
Felis silvestris
Mouse
Mus musculus
P10854
126
13918
S56
V
H
P
D
T
G
I
S
S
K
A
M
G
I
M
Rat
Rattus norvegicus
Q00715
125
13972
S56
V
H
P
D
T
G
I
S
S
K
A
M
G
I
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515176
126
13930
S56
V
H
P
D
T
G
I
S
S
K
A
M
G
I
M
Chicken
Gallus gallus
P0C1H4
126
13932
S56
V
H
P
D
T
G
I
S
S
K
A
M
G
I
M
Frog
Xenopus laevis
P02281
126
13916
S56
V
H
P
D
T
G
I
S
S
K
A
M
S
I
M
Zebra Danio
Brachydanio rerio
Q6PC60
126
13930
S56
V
H
P
D
T
G
I
S
S
K
A
M
G
I
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P04255
122
13482
K54
P
D
T
G
V
S
S
K
A
M
S
I
M
N
S
Sea Urchin
Strong. purpuratus
P02289
124
13598
R56
P
D
T
G
I
S
S
R
A
M
V
I
M
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.2
81.1
90.5
N.A.
98.4
96
N.A.
99.2
96
94.4
94.4
N.A.
N.A.
N.A.
80.1
78.5
Protein Similarity:
100
82.8
81.8
91.9
N.A.
99.2
97.6
N.A.
99.2
97.6
98.4
97.6
N.A.
N.A.
N.A.
88
85.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
17
0
84
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
84
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
17
0
84
0
0
0
0
0
0
75
0
0
% G
% His:
0
84
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
84
0
0
0
0
17
0
84
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
84
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
17
0
84
17
0
84
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% N
% Pro:
17
0
84
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
17
17
84
84
0
9
0
9
0
17
% S
% Thr:
0
0
17
0
84
0
0
0
0
0
0
0
0
0
0
% T
% Val:
84
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _